Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis

P Mistry, MJ Kaplan - Clinical Immunology, 2017 - Elsevier
Nephritis is one of the most severe complications of systemic lupus erythematosus (SLE).
One key characteristic of lupus nephritis (LN) is the deposition of immune complexes …

Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus

SP Crampton, PA Morawski… - Disease models & …, 2014 - journals.biologists.com
Systemic lupus erythematosus (SLE) represents a challenging autoimmune disease from a
clinical perspective because of its varied forms of presentation. Although broad-spectrum …

[HTML][HTML] Protective effects of edible insect protein extracts from Protaetia brevitarsis against H2O2-induced oxidative stress in mouse C2C12 myoblast cells

JH Lee, TK Kim, MC Kang, BK Kim, YS Choi - Food Bioscience, 2023 - Elsevier
Edible insects have been attracting significant attention not only for their nutritional
superiority but also for their excellent bio-functional activity. In this study, the apoptotic …

Induction of apoptosis in HepG2 cells by solanine and Bcl-2 protein

YB Ji, SY Gao, CF Ji, X Zou - Journal of Ethnopharmacology, 2008 - Elsevier
The nightshade (Solanum nigrum Linn.) has been widely used in Chinese traditional
medicine as a remedy for the treatment of digestive system cancer. The anti-tumor activity of …

Biomarkers of drug-induced acute kidney injury in the adult

GC Gobe, JS Coombes, RG Fassett… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: This article addresses general biomarkers of drug-induced acute kidney injury
(AKI) and their application in development and progression of AKI in the adult. It also …

The Antioxidant Activity of Undaria pinnatifida Sporophyll Extract Obtained Using Ultrasonication: A Focus on Crude Polysaccharide Extraction Using Ethanol …

JH Lee, JH Kim, SM Kim, JY Kim, JH Kim, SJ Eom… - Antioxidants, 2023 - mdpi.com
Undaria pinnatifida, a marine biological resource from which antioxidants such as
polysaccharides can be obtained, is primarily distributed in the coastal areas of East Asia …

Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus

FB Vincent, R Kandane-Rathnayake… - Lupus Science & …, 2020 - lupus.bmj.com
Objective Fas/Fas ligand (FasL) and B cell-activating factor (BAFF) signalling have pivotal
roles in SLE pathogenesis. We investigated the clinical associations of serum …

Mesangial cell‐specific antibodies are central to the pathogenesis of lupus nephritis

G Seret, Y Le Meur, Y Renaudineau… - Journal of Immunology …, 2012 - Wiley Online Library
Not only is nephritis a common complaint in systemic lupus erythematosus, but it is also the
most life‐threatening complication of the disease. Anti‐double‐stranded DNA antibodies …

Design of a universal biointerface for sensitive, selective, and multiplex detection of biomarkers using surface plasmon resonance imaging

A Shabani, M Tabrizian - Analyst, 2013 - pubs.rsc.org
This paper reports on the sensitive, selective, and simultaneous detection of four protein
biomarkers involved in metastasis of various cancers, namely Fas, angiopoietin-2 (Ang-2) …

Urinary levels of sirtuin-1 associated with disease activity in lupus nephritis

D Olivares, J Perez-Hernandez, MJ Forner… - Clinical …, 2018 - portlandpress.com
Identifying new markers of disease flares in lupus nephritis (LN) that facilitate patient
stratification and prognosis is important. Therefore, the aim of the present study was to …