Fibrosis in adipose tissue is a major driver of obesity-related metabolic dysregulation. It is
characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy …

Frailty is a common geriatric syndrome characterized by increased vulnerability and is
associated with adverse clinical events such as falls, hospitalization, and death. Early …

The globally increasing prevalence of obesity is associated with the development of
metabolic diseases such as type 2 diabetes, dyslipidemia, and fatty liver. Excess adipose …

Obesity, a global public health concern, is an important risk factor for metabolic diseases
and several cancers. Fibro-inflammation in adipose tissues (ATs) is tightly associated with …

Our overview covers several key areas related to recent results obtained for collagen type VI
and endotrophin (ETP).(1) An introduction to the history of ETP, including how it was …

Background The signalling peptide endotrophin is derived through proteolytic cleavage of
the carboxyl-terminal during formation of type VI collagen. It is expressed by most …

Simple Summary Adipose tissue is considered a metabolic organ that adjusts overall energy
homeostasis and critical hormones to the body's needs. In conditions of caloric intake …

Coronary artery disease (CAD) remains a leading cause of disease burden globally, and
there is a persistent need for new therapeutic targets. Instrumental variable (IV) and genetic …

OBJECTIVE: Bicuspid aortic valve (BAV) is the most common congenital heart defect.
Ascending aorta dilatation is related to BAV-and hypertension (HTN)-associated aortopathy …

Introduction: Collagen 6 is one of the important components of the adipose tissue
extracellular matrix, and its deposition is associated with metabolic disorders. This study …