Obesity and impaired metabolic health are established risk factors for the non-
communicable diseases (NCDs) type 2 diabetes mellitus, cardiovascular disease …

Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Under normal physiological conditions the brain primarily utilizes glucose for ATP
generation. However, in situations where glucose is sparse, eg, during prolonged fasting …

Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …

The brain is a highly energy-demanding organ and requires bioenergetic adaptability to
balance normal activity with pathophysiological fuelling of spontaneous recurrent seizures …

At present, the prevalence of Alzheimer's disease, a devastating neurodegenerative
disorder, is increasing. Although the mechanism of the underlying pathology is not fully …

Despite existing therapy, patients with heart failure (HF) experience substantial morbidity
and mortality, highlighting the urgent need to identify novel pathophysiological mechanisms …

Medium chain fatty acids (MCFAs) has unique transport system and is rapidly metabolized in
the body. It mainly occurs in coconut oil, palm kernel oil and milk products. Dietary …

Migraine is characterized by recurrent attacks of disabling headaches, often accompanied
by sensory and motor disturbances. Clinical manifestations of migraine are influenced by …

Neurovascular integrity, including cerebral blood flow (CBF) and blood-brain barrier (BBB)
function, plays a major role in determining cognitive capability. Recent studies suggest that …