The role of peripheral immune cells in the CNS in steady state and disease
The CNS is protected by the immune system, including cells that reside directly within the
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …
Neuroplastic changes in depression: a role for the immune system
Accumulating evidence suggests that there is a rich cross-talk between the neuroimmune
system and neuroplasticity mechanisms under both physiological conditions and …
system and neuroplasticity mechanisms under both physiological conditions and …
Surveillance, phagocytosis, and inflammation: How never‐resting microglia influence adult hippocampal neurogenesis
A Sierra, S Beccari, I Diaz-Aparicio, JM Encinas… - Neural …, 2014 - Wiley Online Library
Microglia cells are the major orchestrator of the brain inflammatory response. As such, they
are traditionally studied in various contexts of trauma, injury, and disease, where they are …
are traditionally studied in various contexts of trauma, injury, and disease, where they are …
Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing
Two bottlenecks impeding the genetic analysis of complex traits in rodents are access to
mapping populations able to deliver gene-level mapping resolution and the need for …
mapping populations able to deliver gene-level mapping resolution and the need for …
Hippocampal adult neurogenesis: Does the immune system matter?
AS de Miranda, CJ Zhang, A Katsumoto… - Journal of the …, 2017 - Elsevier
Adult hippocampal neurogenesis involves proliferation, survival, differentiation and
integration of newborn neurons into pre-existing neuronal networks. Although its functional …
integration of newborn neurons into pre-existing neuronal networks. Although its functional …
Activated regulatory T cell regulates neural stem cell proliferation in the subventricular zone of normal and ischemic mouse brain through interleukin 10
Recent studies have demonstrated that the depletion of Regulatory T cells (Tregs) inhibits
neural progenitor cell migration after brain ischemia. However, whether Tregs affect neural …
neural progenitor cell migration after brain ischemia. However, whether Tregs affect neural …
The behavioral and immunological impact of maternal separation: a matter of timing
Maternal separation (MS), an early life stressful event, has been demonstrated to trigger
neuropsychiatric disorders later in life, in particular depression. Experiments using rodents …
neuropsychiatric disorders later in life, in particular depression. Experiments using rodents …
Association between serum brain-derived neurotrophic factor and plasma interleukin-6 in major depressive disorder with melancholic features
K Patas, BWJH Penninx, BAA Bus… - Brain, behavior, and …, 2014 - Elsevier
Inflammatory processes as well as attenuation of brain-derived neurotrophic factor (BDNF)
availability are involved in the pathophysiology of major depressive disorder (MDD) …
availability are involved in the pathophysiology of major depressive disorder (MDD) …
Cellular markers of neuroinflammation and neurogenesis after ischemic brain injury in the long-term survival rat model
MRI was employed to follow the neurodegenerative foci and the localization of inflammatory
cells by magnetically labeled CD4+ or CD8+ lymphocytes in the ischemia/reperfusion long …
cells by magnetically labeled CD4+ or CD8+ lymphocytes in the ischemia/reperfusion long …
[HTML][HTML] The architecture of parent-of-origin effects in mice
The number of imprinted genes in the mammalian genome is predicted to be small, yet we
show here, in a survey of 97 traits measured in outbred mice, that most phenotypes display …
show here, in a survey of 97 traits measured in outbred mice, that most phenotypes display …