Eph-Ephrin signaling mediates cross-talk within the bone microenvironment

A Arthur, S Gronthos - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Skeletal integrity is maintained through the tightly regulated bone remodeling process that
occurs continuously throughout postnatal life to replace old bone and to repair skeletal …

EphrinB2–EphB4 Signaling in Neurooncological Disease

A Piffko, C Uhl, P Vajkoczy, M Czabanka… - International journal of …, 2022 - mdpi.com
EphrinB2–EphB4 signaling is critical during embryogenesis for cardiovascular formation
and neuronal guidance. Intriguingly, critical expression patterns have been discovered in …

Early-life exercise primes the murine neural epigenome to facilitate gene expression and hippocampal memory consolidation

AM Raus, TD Fuller, NE Nelson, DA Valientes… - Communications …, 2023 - nature.com
Aerobic exercise is well known to promote neuroplasticity and hippocampal memory. In the
developing brain, early-life exercise (ELE) can lead to persistent improvements in …

Divergent roles of ephrin-B2/EphB4 guidance system in pulmonary hypertension

S Crnkovic, S Rittchen, K Jandl, J Gindlhuber… - …, 2023 - Am Heart Assoc
Background: Smooth muscle cell (SMC) expansion is one key morphological hallmark of
pathologically altered vasculature and a characteristic feature of pulmonary vascular …

A synthetic bivalent peptide ligand of EphB4 with potent agonistic activity

T Fan, B Liang, L Nie, J Wang, H Zhang… - European Journal of …, 2022 - Elsevier
Interaction between ephrin receptor EphB4 and its ligand EFNB2 mediates bidirectional
signaling important for cancer: forward EFNB2-to-EphB4 signaling that is tumor suppressive …

The EPH/ephrin system in gynecological cancers: focusing on the roots of carcinogenesis for better patient management

I Psilopatis, A Pergaris, K Vrettou, G Tsourouflis… - International Journal of …, 2022 - mdpi.com
Gynecological cancers represent some of the most common types of malignancy worldwide.
Erythropoietin-producing hepatocellular receptors (EPHs) comprise the largest subfamily of …

Endothelial EphrinB2 regulates sunitinib therapy response in murine glioma

T Broggini, L Stange, KE Lucia, P Vajkoczy… - Life, 2022 - mdpi.com
Vascular guidance is critical in developmental vasculogenesis and pathological
angiogenesis. Brain tumors are strongly vascularized, and antiangiogenic therapy was …

[HTML][HTML] Ephrin B2 mediates high glucose induced endothelial-to-mesenchymal transition in human aortic endothelial cells

C Yuan, L Ni, C Zhang, H Xia, X Wu - … Diagnosis and Therapy, 2020 - ncbi.nlm.nih.gov
Background Previous study revealed that high glucose (HG) induced endothelial cell (EC)
damage via endothelial-to-mesenchymal transition (EndMT). Recent studies suggested the …

An in vivo, neuron-specific approach for pairing translational and epigenetic signatures of early-life exercise

AM Raus, TD Fuller, NE Nelson, A Bayat… - bioRxiv, 2021 - biorxiv.org
Aerobic exercise promotes physiological and molecular adaptations in neurons to influence
brain function and behavior. The most well studied neurobiological consequences of …

[图书][B] Early-Life Exercise Engages Neural Epigenetic Mechanisms to Enable Hippocampal Memory

AM Raus - 2022 - search.proquest.com
Aerobic exercise is well know to promote neuroplasticity and hippocampal memory. More
recent studies suggest that early-life exercise (EX) can lead to lasting improvements in …