Research progress on biological regulation and biosynthesis of isosteroid alkaloids in Fritillaria

P Qi, Y Zhang, C Zhao, L Sun, R Bai, L Wang… - Plant Growth …, 2023 - Springer
Isosteroidal alkaloids are kinds of alkaloids with unique structures and remarkable activities.
These compounds have important pharmacological activities, such as analgesic …

Transcriptomic and metabolomic reprogramming to explore the high-altitude adaptation of medicinal plants: a review

V Kumar, P Kumar, B Bhargava, R Sharma… - Journal of Plant Growth …, 2023 - Springer
High-altitude climates are characterized by intense solar and UV (ultraviolet) stress, long
periods of sunlight, low temperatures, and a significant temperature differential between day …

Ecological survey, population assessment and habitat distribution modelling for conserving Fritillaria roylei—A critically endangered Himalayan medicinal herb

R Chandora, S Paul, RC Kanishka, P Kumar… - South African Journal of …, 2023 - Elsevier
In the Anthropocene epoch, there is a growing global conservation concern for rare,
endangered, and threatened species owing to their increased vulnerability resulting in small …

Integrated transcriptomic and metabolomic analysis reveals the molecular basis of tissue-specific accumulation of bioactive steroidal alkaloids in Fritillaria …

H Liao, H Quan, B Huang, H Ji, T Zhang, J Chen… - Phytochemistry, 2023 - Elsevier
Fritillaria unibracteata is an endangered medicinal plant whose bulb has been used as a
Chinese herb to suppress cough, asthma and excessive phlegm for centuries. Steroidal …

[HTML][HTML] Integrative analysis of the steroidal alkaloids distribution and biosynthesis of bulbs Fritillariae Cirrhosae through metabolome and transcriptome analyses

Q Lu, R Li, J Liao, Y Hu, Y Gao, M Wang, J Li, Q Zhao - BMC genomics, 2022 - Springer
Abstract Background Bulbus Fritillariae Cirrhosae (BFC) is an endangered high-altitude
medicine and food homology plant with anti-tumor, anti-asthmatic, and antitussive activities …

[HTML][HTML] Transcriptomic and metabolomic analyses provide new insights into the appropriate harvest period in regenerated bulbs of Fritillaria hupehensis

Y Duan, J Wu, F Wang, K Zhang, X Guo… - Frontiers in Plant …, 2023 - frontiersin.org
Introduction The bulb of Fritillaria hupehensis, a traditional cough and expectorant medicine,
is usually harvested from June to September according to traditional cultivation experience …

LED blue light enhances the accumulation and synthesis of steroidal alkaloids in Fritillaria unibracteata Hsiao et KC Hsia in vitro

M Peng, Z Liu, X Chen, Y Xiao, S Wang, Z Yan… - Industrial Crops and …, 2024 - Elsevier
The unique light environment of alpine regions exerts significant influences on the growth,
development, and metabolism of alpine plants, with light quality being a fundamental …

[HTML][HTML] Altitudinal Variation on Metabolites, Elements, and Antioxidant Activities of Medicinal Plant Asarum

L Pan, N Yang, Y Sui, Y Li, W Zhao, L Zhang, L Mu… - Metabolites, 2023 - mdpi.com
Asarum (Asarum sieboldii Miq. f. seoulense (Nakai) CY Cheng et CS Yang) is a medicinal
plant that contains asarinin and sesamin, which possess extensive medicinal value. The …

[HTML][HTML] Transcriptome Analysis of CYP450 Family Members in Fritillaria cirrhosa D. Don and Profiling of Key CYP450s Related to Isosteroidal Alkaloid Biosynthesis

R Li, M Xiao, J Li, Q Zhao, M Wang, Z Zhu - Genes, 2023 - mdpi.com
Fritillaria cirrhosa D. Don (known as Chuan-Bei-Mu in Chinese) can synthesize isosteroidal
alkaloids (ISA) with excellent medicinal value, and its bulb has become an indispensable …

[HTML][HTML] Metabolite profiling and transcriptomic analyses demonstrate the effects of biocontrol agents on alkaloid accumulation in Fritillaria thunbergii

X Cheng, D Li, Z Jiang, C Qu, H Yan, Q Wu - BMC Plant Biology, 2023 - Springer
Abstract Background During Fritillaria thunbergii planting, pests and diseases usually
invade the plant, resulting in reduced yield and quality. Previous studies have demonstrated …