Developing reliable, predictive animal models for complex psychiatric disorders, such as
schizophrenia, is essential to increase our understanding of the neurobiological basis of the …

Schizophrenia is a heterogeneous psychiatric disorder that is poorly treated with current
therapies. In this brief review, we provide an update regarding the use of animal models to …

The origins of schizophrenia have eluded clinicians and researchers since Kraepelin and
Bleuler began documenting their findings. However, large clinical research efforts in recent …

Over the last few decades, advances in human and animal‐based techniques have greatly
enhanced our understanding of the neural mechanisms underlying psychiatric disorders …

The prefrontal cortex (PFC), seat of the highest-order cognitive functions, constitutes a
conglomerate of highly specialized brain areas and has been implicated to have a role in …

Over the last decade, finding a reliable biomarker for the early detection of schizophrenia
(Scz) has been a topic of interest. The main goal of the current review is to provide a …

Schizophrenia is a severe mental illness that afflicts nearly 1% of the world's population.
One of the cardinal pathological features of schizophrenia is perturbation in synaptic …

Transgenic systems are widely used to study the cellular and molecular basis of human
neurodegenerative diseases. A wide variety of model organisms have been utilized …

Schizophrenia has long been considered as a disorder with multifactorial origins. Recent
discoveries have advanced our understanding of the genetic architecture of the disease …

GABA ergic interneurons control the neural circuitry and network activity in the brain. The
advances in genetics have identified genes that control the development, maturation, and …