Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets
R Qin, FM You, Q Zhao, X Xie, C Peng, G Zhan… - Journal of hematology & …, 2022 - Springer
Regulated cell death (RCD) is a critical and active process that is controlled by specific
signal transduction pathways and can be regulated by genetic signals or drug interventions …
signal transduction pathways and can be regulated by genetic signals or drug interventions …
Anti-tubulin agent vinorelbine inhibits metastasis of cancer cells by regulating epithelial-mesenchymal transition
H Liu, Q Fu, Y Lu, W Zhang, P Yu, Z Liu… - European Journal of …, 2020 - Elsevier
Cancer invasion and metastasis are the leading causes of death. The process of metastasis
or tumor cell dissemination is still much of a mystery. Emerging evidence has shown that …
or tumor cell dissemination is still much of a mystery. Emerging evidence has shown that …
IFN‑γ induces apoptosis in gemcitabine‑resistant pancreatic cancer cells
X Kong, D Cheng, X Xu… - Molecular Medicine …, 2024 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent and aggressive form of
pancreatic cancer. Gemcitabine (GEM), the first‑line treatment for PDAC, which alleviates …
pancreatic cancer. Gemcitabine (GEM), the first‑line treatment for PDAC, which alleviates …
[HTML][HTML] Correlation between expression of epidermal growth factor receptor and adverse reactions after chemotherapy of advanced non-small-cell lung cancer
Z Hao, C Tian, F Yang, J Zhang - Pakistan Journal of Medical …, 2015 - ncbi.nlm.nih.gov
Objective: To analyze the correlation between expression of epidermal growth factor
receptor (EGFR) and adverse reactions after chemotherapy of advanced non-small-cell lung …
receptor (EGFR) and adverse reactions after chemotherapy of advanced non-small-cell lung …
TRAIL predisposes non-small cell lung cancer to ferroptosis by regulating ASK-1/JNK1 pathway
X Liu, H Deng, M Huang, W Zhou, Y Yang - Discover Oncology, 2024 - Springer
Objective Our current study aimed to assess the relationship between TNF-related apoptosis-
inducing ligand (TRAIL) and ferroptosis in non-small cell lung cancer (NSCLC) …
inducing ligand (TRAIL) and ferroptosis in non-small cell lung cancer (NSCLC) …
RNA-Seq and network analysis revealed interacting pathways in TGF-β-treated lung cancer cell lines
Y Li, O Rouhi, H Chen, R Ramirez… - Cancer …, 2014 - journals.sagepub.com
Whole transcriptome shotgun sequencing (RNA-Seq) is a useful tool for analyzing the
transcriptome of a biological sample. With appropriate statistical and bioinformatic …
transcriptome of a biological sample. With appropriate statistical and bioinformatic …
Tumor necrosis factor-related apoptosis-inducing ligand modulates angiogenesis and apoptosis to inhibit non-small cell lung carcinoma tumor growth in mice
Y Chen, Y Xu, K Zhu, Z Cao… - Journal of International …, 2019 - journals.sagepub.com
Objective To investigate the anti-tumor effect and mechanism of tumor necrosis factor-
related apoptosis-inducing ligand (TRAIL) in non-small cell lung carcinoma (NSCLC) in …
related apoptosis-inducing ligand (TRAIL) in non-small cell lung carcinoma (NSCLC) in …
Three new compounds with nitric oxide inhibitory activity from Tirpitzia sinensis, an ethnomedicinal plant from Southwest China
The medicinal plant Tirpitzia sinensis has been used by the Zhuang ethnic people in
mountainous areas of Southwest China to stop bleeding, invigorate blood circulation, and …
mountainous areas of Southwest China to stop bleeding, invigorate blood circulation, and …
靶向IGF-1R 的siRNA 增强肺癌细胞对Trail 诱导凋亡敏感性的研究
刘黎明, 胡俊锋, 张永, 夏雪梅, 宫蓓蕾, 曹大龙 - 中华全科医学, 2016 - zhqkyx.net
目的研究IGF-1R 特异RNA 干扰后肺腺癌细胞A549 增殖和凋亡的改变以及其对Trail 的敏感性.
方法化学合成IGF-1R 特异siRNA 转录模板, 与表达载体连接, 转染大肠杆菌扩增后提取质粒 …
方法化学合成IGF-1R 特异siRNA 转录模板, 与表达载体连接, 转染大肠杆菌扩增后提取质粒 …
[PDF][PDF] Studying the chemosensitizing effect of Pirfenidone in non-small cell lung cancer cell lines
HI de Freitas Branco - 2021 - repositorio-aberto.up.pt
Lung cancer is the leading cause of cancer-related deaths worldwide and non-small cell
lung cancer (NSCLC) accounts for roughly 85% of the cases. Despite the advances that …
lung cancer (NSCLC) accounts for roughly 85% of the cases. Despite the advances that …