Progress in the Chemistry of Tetrahydroquinolines

I Muthukrishnan, V Sridharan, JC Menendez - Chemical reviews, 2019 - ACS Publications
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

Medicinal attributes of 1, 2, 3-triazoles: Current developments

D Dheer, V Singh, R Shankar - Bioorganic Chemistry, 2017 - Elsevier
Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …

Quinolines: Microwave-assisted synthesis and their antifungal, anticancer and radical scavenger properties

NA Liberto, JB Simões, S de Paiva Silva… - Bioorganic & medicinal …, 2017 - Elsevier
An efficient method for the synthesis of quinolines using microwave irradiation was
developed providing 28 quinolines with good yields. The reaction procedures are …

Metal complex catalysis in the synthesis of quinolines

RI Khusnutdinov, AR Bayguzina… - Journal of Organometallic …, 2014 - Elsevier
This review integrates and gives analysis of published data about the synthesis of
quinolines by the reactions of anilines with aldehydes, alkenes, alkynes, alkyl amines, allyl …

Synthetic routes to quinoline-based derivatives having potential anti-bacterial and anti-fungal properties

S Sharma, S Singh - Current Organic Chemistry, 2022 - benthamdirect.com
Quinoline and its derivatives are part of several natural products. Many of them are active
pharmacophores and show enormous biological activities. Owing to their usefulness in drug …

Recent synthetic efforts in the preparation of 2-(3, 4)-alkenyl (aryl) quinoline molecules towards anti-kinetoplastid agents

D Orozco, VV Kouznetsov, A Bermúdez, LYV Méndez… - Rsc Advances, 2020 - pubs.rsc.org
Leishmaniasis, Chagas disease and African sleeping sickness have been considered some
of the most important tropical protozoan afflictions. As the number of drugs currently …

Novel N‐allyl/propargyl tetrahydroquinolines: Synthesis via Three‐component Cationic Imino Diels–Alder Reaction, Binding Prediction, and Evaluation as …

YA Rodríguez, M Gutiérrez, D Ramírez… - Chemical biology & …, 2016 - Wiley Online Library
New N‐allyl/propargyl 4‐substituted 1, 2, 3, 4‐tetrahydroquinolines derivatives were
efficiently synthesized using acid‐catalyzed three components cationic imino Diels–Alder …

Synthesis of substituted 4-hydroxyalkyl-quinoline derivatives by a three-component reaction using CuCl/AuCl as sequential catalysts

KM Jiang, JA Kang, Y Jin, J Lin - Organic Chemistry Frontiers, 2018 - pubs.rsc.org
A new method to construct 4-hydroxyalkyl-quinoline derivatives is described via Cu (I) and
Au (I) sequential catalyzed cyclization of anilines with aldehyde derivatives and aliphatic …

Hetero-bimetallic cooperative catalysis for the synthesis of heteroarenes

GR Gupta, J Shah, KS Vadagaonkar… - Organic & …, 2019 - pubs.rsc.org
Multi-metallic cooperative catalysis has gained a lot of interest in organic synthesis over the
past few years exploring various organic transformations. Of all the myriad chemical …

AgNO 3-catalyzed direct C–H arylation of quinolines by oxidative decarboxylation of aromatic carboxylic acids

JW Yuan, LR Yang, P Mao, LB Qu - Organic Chemistry Frontiers, 2017 - pubs.rsc.org
An efficient silver-catalyzed intermolecular decarboxylative arylation of quinolines has been
developed using cheap aromatic carboxylic acids as arylating reagents under microwave …