Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential

TY Zhu, LL Hong, ZQ Ling - Biomarker research, 2023 - Springer
Abstract N6-methyladenosine (m6A) is the most prevalent and well-characterized internal
chemical modification in eukaryotic RNA, influencing gene expression and phenotypic …

Serum autoantibodies as biomarkers for early cancer detection

HT Tan, J Low, SG Lim, MCM Chung - The FEBS journal, 2009 - Wiley Online Library
Autoantibodies against autologus tumor‐associated antigens have been detected in the
asymptomatic stage of cancer and can thus serve as biomarkers for early cancer diagnosis …

The roles of insulin‐like growth factor 2 mRNA‐binding protein 2 in cancer and cancer stem cells

J Cao, Q Mu, H Huang - Stem cells international, 2018 - Wiley Online Library
RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

Serologic autoantibodies as diagnostic cancer biomarkers—a review

P Zaenker, MR Ziman - Cancer Epidemiology, Biomarkers & Prevention, 2013 - AACR
Current diagnostic techniques used for the early detection of cancers are successful but
subject to detection bias. A recent focus lies in the development of more accurate diagnostic …

Developments in point-of-care diagnostic technology for cancer detection

B Hayes, C Murphy, A Crawley, R O'Kennedy - Diagnostics, 2018 - mdpi.com
Cancer is the cause of death for one in seven individuals worldwide. It is widely
acknowledged that screening and early diagnosis are of vital importance for improving the …

Autoantibodies as diagnostic and prognostic cancer biomarker: Detection techniques and approaches

S Yadav, N Kashaninejad, MK Masud… - Biosensors and …, 2019 - Elsevier
Autoantibodies produced by the patients' own immune systems in response to foreign
substances are emerging as an attractive biomarker for early detection of cancer. These …

Role of miR-21 in the diagnosis of colorectal cancer: Meta-analysis and bioinformatics

J Li, H Chen, G Sun, X Zhang, H Ye, P Wang - Pathology-Research and …, 2023 - Elsevier
Advanced colorectal cancer (CRC) has a bad prognosis and is challenging to cure.
Therefore, there is an urgent need for an effective early diagnosis marker. MicroRNA-21 …

[HTML][HTML] IMP3 overexpression occurs in various important cancer types and is linked to aggressive tumor features: A tissue microarray study on 8,877 human cancers …

C Burdelski, N Jakani-Karimi… - Oncology …, 2018 - spandidos-publications.com
IMP3 is an RNA binding protein required for ribosomal RNA processing, which has been
suggested to be a prognostic marker in a large variety of human types of cancer. However …

Blood autoantibodies against tumor-associated antigens as biomarkers in early detection of colorectal cancer

H Chen, S Werner, S Tao, I Zoernig, H Brenner - Cancer letters, 2014 - Elsevier
Multiple studies have shown that cancer patients produce detectable autoantibodies against
certain tumor-associated antigens, which might be promising blood biomarkers for early …

Recent advances on immune targeted therapy of colorectal cancer using bi-specific antibodies and therapeutic vaccines

A Azadi, A Golchini, S Delazar… - Biological Procedures …, 2021 - Springer
Colorectal cancer (CRC) is a universal heterogeneous disease that is characterized by
genetic and epigenetic alterations. Immunotherapy using monoclonal antibodies (mAb) and …