Abstract Single‐crystal‐to‐single‐crystal (SCSC) phase transitions are direct structural
evolutions of crystalline materials in the solid state without the damage of ordering in the …

Indomethacin is a clinically classical non‐steroidal anti‐inflammatory drug that has been
marketed since 1965. The third polymorph, Form δ, was discovered by both melt and …

Polymorphism occurs widely in pharmaceutical solids, and must be thoroughly studied
during product development. Twenty-four years after ritonavir (RTV) Form II materialized, we …

Polymorphism, the ability of the same substance to crystallize in more than one crystal
structure, is a common phenomenon in organic crystals, influencing the physicochemical …

Crystal nucleation rates have been measured in the supercooled melts of two richly
polymorphic glass-forming liquids: ROY and nifedipine (NIF). ROY or 5-methyl-2-[(2 …

Two new polymorphs of piroxicam (Forms VI and VII) were discovered by melt crystallization
and crystal structure prediction (CSP). High-quality single crystals were grown from melt …

The ability of molecules to move and rearrange in the solid state accounts for the
polymorphic transition and stimuli-responsive properties of molecular crystals. However …

Amorphous formulations, increasingly employed to deliver poorly soluble drugs, generally
contain surfactants to improve wetting and dissolution. These surfactants are often liquids …

Controlling different types of forces to achieve materials with different emission responses
remains a challenge. In this work, polymorphic organic crystals with blue (1-B) and green (1 …

For a pair of hydrated and anhydrous crystals, the hydrate is more stable than the anhydrate
when the water activity is above the critical water activity (a wc). Conventional methods to …