[HTML][HTML] Polymer based sustained drug delivery to the ocular posterior segment: barriers and future opportunities for the treatment of neovascular pathologies

RA Alshaikh, C Waeber, KB Ryan - Advanced Drug Delivery Reviews, 2022 - Elsevier
There is an increasing momentum in research and pharmaceutical industry communities to
design sustained, non-invasive delivery systems to treat chronic neovascular ocular …

Suprachoroidally injected pharmacological agents for the treatment of chorioretinal diseases: a targeted approach

Z HabotWilner, G Noronha, CC Wykoff - Acta ophthalmologica, 2019 - Wiley Online Library
Delivery of pharmaceuticals to the posterior segment presents challenges that arise from the
anatomy and clearance pharmacokinetics of the eye. Systemic and several local …

Strategies for modifying drug residence time and ocular bioavailability to decrease treatment frequency for back of the eye diseases

W Shatz, J Aaronson, S Yohe, RF Kelley… - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: Treating posterior eye diseases has become a major area of focus for
pharmaceutical and biotechnology companies. Current standard of care for treating …

Novel therapies in development for diabetic macular edema

A Agarwal, R Afridi, M Hassan, MA Sadiq… - Current diabetes …, 2015 - Springer
Diabetic macular edema (DME) secondary to diabetic retinopathy (DR) is a major cause for
functional visual loss in the developed world. Laser photocoagulation has been used for …

Current drug and molecular therapies for the treatment of atrophic age-related macular degeneration: phase I to phase III clinical development

H Li, SR Chintalapudi, MM Jablonski - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Age-related macular degeneration (AMD) is the leading cause of vision loss
among the elderly. Atrophic AMD, including early, intermediate and geographic atrophy …

Solid lipid nanoparticles improve the diclofenac availability in vitreous after intraocular injection

M Abrishami, M Abrishami, A Mahmoudi… - Journal of drug …, 2016 - Wiley Online Library
Purpose. In order to improve the drug availability after intravitreal administration, solid lipid
nanoparticles (SLNs) containing diclofenac were prepared. Methods. In this experimental …

Corticosteroid-Induced Glaucoma

J Liu, CA Arrigg - Albert and Jakobiec's Principles and Practice of …, 2022 - Springer
Corticosteroid use has been found as a risk factor for ocular hypertension and glaucoma
since 1950s. The effect of corticosteroids on intraocular pressure varies depending on their …

Nonbiological pharmacotherapies for the treatment of diabetic macular edema

A Agarwal, J Parriott, S Demirel, C Argo… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: During the past decade, there have been significant advances in the
pharmacotherapies for the treatment of diabetic macular edema (DME). Among the presently …

Advances in Intravitreal Therapeutics in Uveitis

PD Majumder, J Biswas - Gems of Ophthalmology: Diseases of …, 2018 - books.google.com
Uveitis is often chronic and potentially sight-threatening disorder and because of the chronic
nature of the inflammation and associated risks of complications, the treatment of uveitis …

[PDF][PDF] Research Article Solid Lipid Nanoparticles Improve the Diclofenac Availability in Vitreous after Intraocular Injection

M Abrishami, M Abrishami, A Mahmoudi, N Mosallaei… - 2016 - academia.edu
Purpose. In order to improve the drug availability after intravitreal administration, solid lipid
nanoparticles (SLNs) containing diclofenac were prepared. Methods. In this experimental …