[HTML][HTML] The human connectome project: a retrospective

JS Elam, MF Glasser, MP Harms, SN Sotiropoulos… - NeuroImage, 2021 - Elsevier
Abstract The Human Connectome Project (HCP) was launched in 2010 as an ambitious
effort to accelerate advances in human neuroimaging, particularly for measures of brain …

Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight

JW Vogel, N Corriveau-Lecavalier… - Nature Reviews …, 2023 - nature.com
Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

[HTML][HTML] Geometric constraints on human brain function

JC Pang, KM Aquino, M Oldehinkel, PA Robinson… - Nature, 2023 - nature.com
The anatomy of the brain necessarily constrains its function, but precisely how remains
unclear. The classical and dominant paradigm in neuroscience is that neuronal dynamics …

Standardizing workflows in imaging transcriptomics with the abagen toolbox

RD Markello, A Arnatkeviciute, JB Poline, BD Fulcher… - elife, 2021 - elifesciences.org
Gene expression fundamentally shapes the structural and functional architecture of the
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …

Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder

AM Buch, PE Vértes, J Seidlitz, SH Kim… - Nature …, 2023 - nature.com
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Epilepsy and brain network hubs

J Royer, BC Bernhardt, S Larivière, E Gleichgerrcht… - …, 2022 - Wiley Online Library
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

[HTML][HTML] BrainStat: A toolbox for brain-wide statistics and multimodal feature associations

S Larivière, Ş Bayrak, RV de Wael, O Benkarim… - NeuroImage, 2023 - Elsevier
Abstract Analysis and interpretation of neuroimaging datasets has become a
multidisciplinary endeavor, relying not only on statistical methods, but increasingly on …

Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders

MD Hettwer, S Larivière, BY Park… - Nature …, 2022 - nature.com
Neuropsychiatric disorders are increasingly conceptualized as overlapping spectra sharing
multi-level neurobiological alterations. However, whether transdiagnostic cortical alterations …

Integrating multimodal and multiscale connectivity blueprints of the human cerebral cortex in health and disease

JY Hansen, G Shafiei, K Voigt, EX Liang, SML Cox… - PLoS …, 2023 - journals.plos.org
The brain is composed of disparate neural populations that communicate and interact with
one another. Although fiber bundles, similarities in molecular architecture, and synchronized …

Modeling spatial, developmental, physiological, and topological constraints on human brain connectivity

S Oldham, BD Fulcher, K Aquino, A Arnatkevičiūtė… - Science …, 2022 - science.org
The complex connectivity of nervous systems is thought to have been shaped by competitive
selection pressures to minimize wiring costs and support adaptive function. Accordingly …