We carried out systematic review and meta-analysis to evaluate whether peripheral levels of
pro-inflammatory markers including Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), Tumor …

Abstract Context Elevation of homocysteine (Hcy) levels is well-established as a risk factor
for dementia, yet controversy exists regarding whether B-vitamin-mediated reduction of …

Blood-based biomarkers present a considerable challenge: technically, as blood is a
complex tissue and conceptually, as blood lacks direct contact with brain. Nonetheless …

The associations between homocysteine (Hcy), folic acid, and vitamin B12 and Alzheimer's
disease (AD) have gained much interest, while remaining controversial. We aim to perform …

Background Elevated plasma homocysteine​​(Hcy) levels have been associated with
cognitive dysfunction in a wide range of conditions. The aim of this review is to establish …

There is some debate regarding the differing levels of plasma homocysteine, vitamin B12
and serum folate between healthy controls (HC), mild cognitive impairment (MCI), and …

Inflammation may be associated with Alzheimer's disease (AD). This meta-analysis aimed to
compare the level of C-reactive protein (CRP) in patients having AD to healthy controls. A …

Background Numerous studies have indicated the role of inflammation in the pathogenesis
of Alzheimer's disease (AD). However, the exact role of inflammatory markers in AD is still …

Although recent studies suggest homocysteine (Hcy) is an independent risk factor for
neurodegenerative disorders, little is known about sex differences in the levels of Hcy. In this …

Introduction and objective. Evidence for the benefit of antioxidants' based therapeutic
intervention in dementia are inconsistent. Parallel studies in disease forms of dementia …