Edaravone alleviates methotrexate-induced testicular injury in rats: Implications on inflammation, steroidogenesis, and Akt/p53 signaling

EHM Hassanein, WR Mohamed, RM Hussein… - International …, 2023 - Elsevier
Edaravone (ED) is a neuroprotective drug with beneficial effects against several disorders
due to its prominent antioxidant activity. However, its effect against methotrexate (MTX) …

Ferritinophagy-mediated ferroptosis of spermatogonia is involved in busulfan-induced oligospermia in the mice

J Xu, L Zhang, Y Si, W Huang, R Liu, Z Liu… - Chemico-Biological …, 2024 - Elsevier
Busulfan, a bifunctional alkylated chemotherapeutic agent, has male reproductive toxicity
and induce oligospermia, which is associated with ferroptosis. However, the specific target …

The impact of busulfan on the testicular structure in prepubertal rats: A histological, ultrastructural and immunohistochemical study

RI Abd El-Hay, WHE Hamed… - Ultrastructural …, 2023 - Taylor & Francis
Busulfan is a widely used cancer chemotherapeutic agent. Temporary or permanent sterility
in male patients is one of the most common side effects of this drug. The present study was …

Chronic Administration of Lisdexamfetamine Induces Apoptosis and Inflammation and Reduces Sperm Quality in Adult Male Rats

S Roustaee, M Sani, M Mehranpour, P Raee… - Reproductive …, 2024 - Springer
Concerns have been raised about potentially irreversible brain damage and damage to the
neuroendocrine system during development when treating attention-deficit/hyperactivity …

An elderberry-supplemented diet improves spermatogenesis in mice with busulfan-induced azoospermia

MM Balani, MG Novin, MS Alvani, P Raee… - Reproduction …, 2022 - CSIRO Publishing
Context Approximately 40–50% of all infertility cases are due to male infertility, and one of
the most important causes of infertility is azoospermia. Aims This study aimed to evaluate the …

Therapeutic Effects of Edar avone on Azoospermia: Free Radical Scavenging and Autophagy Modulation in Testicular Tissue of M

NM Ghaffari, AM Sabbagh, BM Mafi, A Aliaghaei… - 2022 - sid.ir
Background: Chemotherapeutic agents such as cyclophosphamide and Busulfan have been
shown to have a negative impact on the spermatogenesis process. Based on this fact, the …

[引用][C] Maternal exposure to phenanthrene induces testicular apoptosis and Sertoli cell dysfunction in F1 adult male mice: a histological and molecular study

A Afshar, H Nazarian, F Fadaefathabadi… - Korean Journal of …, 2024 - ecerm.org
Maternal exposure to phenanthrene induces testicular apoptosis and Sertoli cell
dysfunction in F1 adult male mice: a histological and molecular study Home E-submission …