Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
Pharmacological significance of nitrogen-containing five and six-membered heterocyclic scaffolds as potent cholinesterase inhibitors for drug discovery
N-heterocycles are crucial due to their biological, chemical, and practical significance. They
are heavily investigated in biological processes involving anticancer, anti-inflammatory …
are heavily investigated in biological processes involving anticancer, anti-inflammatory …
[HTML][HTML] Advancement of chitin and chitosan as promising biomaterials
MM Al-Rooqi, MM Hassan, Z Moussa, RJ Obaid… - Journal of Saudi …, 2022 - Elsevier
Biopolymers like cellulose, polysaccharides, chitosan, starch, chitin, and alginates have
sparked an increasing curiosity in creating natural replacements for synthetic polymers …
sparked an increasing curiosity in creating natural replacements for synthetic polymers …
[HTML][HTML] In vitro and in silico evaluation of the antimicrobial and antioxidant activities of spiropyrazoline oxindole congeners
M Chalkha, K Chebbac, H Nour, A Nakkabi… - Arabian Journal of …, 2024 - Elsevier
The search for novel powerful antimicrobial and antioxidant agents is considered a dynamic
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
Novel cis‐Pt (II) Complexes with Alkylpyrazole Ligands: Synthesis, Characterization, and Unusual Mode of Anticancer Action
J Kasparkova, H Kostrhunova… - Bioinorganic …, 2022 - Wiley Online Library
One concept of improving anticancer effects of conventional platinum‐based antitumor
drugs consists of conjugating these compounds with other biologically (antitumor) active …
drugs consists of conjugating these compounds with other biologically (antitumor) active …
New Imidazole-Based N-Phenylbenzamide Derivatives as Potential Anticancer Agents: Key Computational Insights
An efficient atom-economical synthetic protocol to access new imidazole-based N-
phenylbenzamide derivatives is described. A one-pot three-component reaction was utilized …
phenylbenzamide derivatives is described. A one-pot three-component reaction was utilized …
Role of pharmacological active phthalazine scaffolds in medicinal chemistry
SMN Sakib - Open Science Foundation, 2023 - osf.io
Phthalazine derivatives have recently received a lot of interest in the realm of physiologically
active chemical research. Introduce this phthalazine moiety to a researcher in a new …
active chemical research. Introduce this phthalazine moiety to a researcher in a new …
[HTML][HTML] Ionic liquid mediated four-component synthesis of novel phthalazinone based indole-pyran hybrids as cytotoxic agents
MS Malik, RI Alsantali, MA Alsharif, SI Aljayzani… - Arabian Journal of …, 2022 - Elsevier
A robust design and synthesis of novel phthalazinone based indole-pyran hybrids as
cytotoxic agents is described. A relatively safer ionic liquid medium ([BMIM] BF 4) was …
cytotoxic agents is described. A relatively safer ionic liquid medium ([BMIM] BF 4) was …
Design, synthesis, molecular docking, ADMET studies, and biological activity evaluation of new 2-({[3-aryl-1, 2, 4-oxadiazol-5-yl) methyl] thio}-1H-benzimidazoles and …
M Sharaf, AH Moustafa, RJ Obaid… - Journal of Molecular …, 2024 - Elsevier
Aryl amidoximes are active binucleophilic compounds used as a powerful and versatile
reagent in synthesizing diverse heterocyclic compounds with pharmacological interest …
reagent in synthesizing diverse heterocyclic compounds with pharmacological interest …
Antibacterial Properties and Computational Insights of Potent Novel Linezolid-Based Oxazolidinones
The mounting evidence of bacterial resistance against commonly prescribed antibiotics
warrants the development of new antibacterial drugs on an urgent basis. Linezolid, an …
warrants the development of new antibacterial drugs on an urgent basis. Linezolid, an …