Recent aspects of the effects of zinc on human health

CT Chasapis, PSA Ntoupa, CA Spiliopoulou… - Archives of …, 2020 - Springer
Zinc (Zn) is one of the most important essential nutrients of great public health significance. It
is involved in numerous biological functions and it is considered as a multipurpose trace …

The genomic architecture of metastasis in breast cancer: focus on mechanistic aspects, signalling pathways and therapeutic strategies

Y Chhichholiya, P Suman, S Singh, A Munshi - Medical Oncology, 2021 - Springer
Breast cancer is a multifactorial, heterogeneous disease and the second most frequent
cancer amongst women worldwide. Metastasis is one of the most leading causes of death in …

Allicin induces cell cycle arrest and apoptosis of breast cancer cells in vitro via modulating the p53 pathway

G Maitisha, M Aimaiti, Z An, X Li - Molecular Biology Reports, 2021 - Springer
Background The tumor suppressor protein p53 is a most promising target for the
development of anticancer drugs. Allicin (diallylthiosulfinate) is one of the most active …

Therapeutic applications of CRISPR/Cas9 in breast cancer and delivery potential of gold nanomaterials

J Padayachee, M Singh - Nanobiomedicine, 2020 - journals.sagepub.com
Globally, approximately 1 in 4 cancers in women are diagnosed as breast cancer (BC).
Despite significant advances in the diagnosis and therapy BCs, many patients develop …

UDP-glucose 6-dehydrogenase knockout impairs migration and decreases in vivo metastatic ability of breast cancer cells

ST Teoh, MP Ogrodzinski, SY Lunt - Cancer Letters, 2020 - Elsevier
Dysregulated metabolism is a hallmark of cancer that supports tumor growth and metastasis.
One understudied aspect of cancer metabolism is altered nucleotide sugar biosynthesis …

Design, synthesis and biological evaluation of water soluble and non-aggregated silicon phthalocyanines, naphthalocyanines against A549, SNU-398, SK-MEL128 …

T Keleş, B Barut, A Özel, Z Biyiklioglu - Bioorganic Chemistry, 2021 - Elsevier
Cancer has become an important public problem in worldwide since cancer incidence and
mortality are growing rapidly. In this study, water soluble and non-aggregated silicon (IV) …

The effect of human umbilical cord mesenchymal stem cells conditioned medium combined with tamoxifen drug on BRCA1 and BRCA2 expression in breast cancer …

AR Panahandeh, M Delashoub, SF Aval - Molecular Biology Reports, 2024 - Springer
Background A growing number of studies has indicated that the expression of Breast Cancer
Susceptibility Genes 1 (BRCA1) and BRCA2 contribute to the resistance to DNA-damaging …

[HTML][HTML] Optimised multiple data partitions for cluster-wise imputation of missing values in gene expression data

S Yosboon, N Iam-On, T Boongoen, P Keerin… - Expert Systems with …, 2024 - Elsevier
It is commonly agreed that the quality of data analysis may be degraded by the presence of
missing data. In various domains such as bioinformatics, an effective tool is required for the …

Gender differential transcriptome in gastric and thyroid cancers

A Sousa, M Ferreira, C Oliveira, PG Ferreira - Frontiers in Genetics, 2020 - frontiersin.org
Cancer has an important and considerable gender differential susceptibility confirmed by
several epidemiological studies. Gastric (GC) and thyroid cancer (TC) are examples of …

Circulating miRNAs as early indicators of diet and physical activity response in women with metastatic breast cancer

J Olson, P Sheean, L Matthews, CR Chitambar… - Future science …, 2021 - Taylor & Francis
Treatments for metastatic breast cancer (MBC) improve survival but often impose prolonged
symptom burden. We performed molecular characterization of 84 miRNAs in the circulating …