Drug-induced gingival overgrowth (DIGO) is one of the side effects produced by therapeutic
agents, most commonly phenytoin, nifedipine and cyclosporin A. However, the precise …

Drug-induced gingival overgrowth is a tissue-specific condition and is estimated to affect
approximately one million North Americans. Lesions occur principally as side-effects from …

Connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61) are prototypical
members of the CCN family which also contains nephroblastoma overexpressed (NOV) and …

Le facteur de croissance du tissu conjonctif (CTGF, CCN2), un membre de la famille des
protéines CCN, est une protéine de la matrice cellulaire pro-adhésive riche en cystéine qui …

Connective tissue growth factor (CTGF/CCN2) is a highly profibrogenic molecule which is
overexpressed in many fibrotic lesions, including those of the liver. CTGF/CCN2 is …

The statin family of drugs are safe and effective therapeutic agents for the treatment of
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …

Gingival overgrowth occurs mainly as a result of certain anti-seizure, immunosuppressive, or
antihypertensive drug therapies. Excess gingival tissues impede oral function and are …

Gingival fibromatosis is a rare and heterogeneous group of disorders that develop as slowly
progressive, local or diffuse enlargements within marginal and attached gingiva or …

Pyogenic granuloma (PG) is a benign vascular lesion found predominantly in the oral cavity.
Characterized by rapid growth and propensity to bleed, PG presents diagnostic challenges …

The CCN family currently comprises six members (CCN1-6) that regulate diverse cell
functions, including mitogenesis, adhesion, apoptosis, extracellular matrix (ECM) …