Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …

Peroxisome proliferator-activated receptor gamma (PPARγ) has been the focus of intense
research because ligands for this receptor have emerged as potent insulin sensitizers used …

Background: Recent studies point to the adipose tissue as a highly active endocrine organ
secreting a range of hormones. Leptin, ghrelin, adiponectin, and resistin are considered to …

Resistin is a cysteine-rich protein postulated to be a molecular link between obesity and type
2 diabetes. The aim of this study was to investigate the role of PPARγ in the regulation of …

Resistin was originally described as an adipocyte-secreted peptide that induced insulin
resistance in rodents. Increasing evidence indicates its important regulatory roles in various …

Insulin resistance is defined as a failure of target organs to respond normally to the action of
insulin. Insulin resistance causes incomplete suppression of hepatic glucose output and …

Obesity is a major risk factor for insulin resistance and type 2 diabetes mellitus. Adipocytes
secrete numerous substances that might contribute to peripheral insulin sensitivity. These …

Resistin is a novel adipocyte-secreted hormone proposed to link obesity with diabetes.
Studies in mice have revealed conflicting data however, and the physiological role of …

Adiponectin is a plasma protein expressed exclusively in adipose tissue. Adiponectin levels
are linked to insulin sensitivity, but a direct effect of chronically elevated adiponectin on …

It has long been known that obesity and insulin resistance are linked. Recently, it has been
shown that adipocytes secrete several proteins including tumour necrosis factor-α …