Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Activated microglia are an important type of innate immune cell in the brain, and they secrete
inflammatory cytokines into the extracellular milieu, exert neurotoxicity to surrounding …

Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction.
Knowledge of the pathophysiology of organ failure in sepsis is crucial for optimizing the …

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. Recently was been found that pyroptosis is a unique form of …

Pyroptosis, a form of programmed cell death, has garnered increasing attention as it relates
to innate immunity and diseases. The discovery of caspase-1/3/4/5/8/11 function in sensing …

Pyroptosis is an inflammatory form of cell death that not only protects multicellular organisms
from invading pathogenic bacteria and microbial infections, but can also lead to sepsis and …

The two oxidation states of ceria nanoparticles, Ce3+ and Ce4+, play a pivotal role in
scavenging reactive oxygen species (ROS). In particular, Ce3+ is largely responsible for …

Abstract Gasdermin‐D (GSDMD), a member of the gasdermin protein family, mediates
pyroptosis in human and murine cells. Cleaved by inflammatory caspases, GSDMD inserts …

Sepsis is defined as organ dysfunction due to a dysregulated systemic host response to
infection. During gram-negative bacterial infection and other acute illness such as …