Our recent survey of genes regulated by insulin/IGF-1 signaling (IIS) in Caenorhabditis
elegans suggests a role for a number of gene classes in longevity assurance. Based on …

Page 1 SETTING LIMITS MEDICAL GOALS IN AN AGING SOCIETY WITH "A RESPONSE TO
MY CRITICS” DANIEL CALLAHAN Page 2 Page 3 SETTING LIMITS This One CEZ8-RX9-YWCO …

The idea that we have an unlimited moral imperative to pursue medical research is deeply
rooted in American society and medicine. In this provocative work, Daniel Callahan exposes …

The social consequences of extending the human life span might be quite bad; perhaps the
worst outcome is that power could be concentrated into ever fewer hands, as those who …

In this paper, I will argue that ageing can be construed as disease. First, the concept of
disease is discussed, where the distinction is made between two lines of thought, an …

An examination of the ethical issues raised by the possibility of human life extension,
including its desirability, unequal access, and the threat of overpopulation. Life extension …

Ageing is often deemed bad for people and something that ought to be eliminated. An
important aspect of this normative aspect of ageing is whether ageing, ie, senescence, is a …

We are pleased to publish two essays presented at that symposium: the pungent and
remarkable essay by Leonard Hayflick, pioneering gerontologist who has made many …

In the philosophical debate on aging, it is common to raise the question of the theoretical
definition of aging in terms of its possible characterization as a disease. Understanding …

The quest to live much longer has moved from legend to the laboratory. Recent
breakthroughs in genetics and pharmacology have put humanity on the precipice of slowing …