[HTML][HTML] Tumor microenvironment in head and neck squamous cell carcinoma: Functions and regulatory mechanisms

G Wang, M Zhang, M Cheng, X Wang, K Li, J Chen… - Cancer Letters, 2021 - Elsevier
The tumor microenvironment has been recently reported to play a pivotal role in sustaining
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …

Current and future biomarkers for immune checkpoint inhibitors in head and neck squamous cell carcinoma

JC Park, HN Krishnakumar, SV Saladi - Current Oncology, 2022 - mdpi.com
With the introduction of immunotherapy, significant improvement has been made in the
treatment of head and neck squamous cell carcinoma (HNSCC). However, only a small …

Association of TP53 and CDKN2A Mutation Profile with Tumor Mutation Burden in Head and Neck Cancer

AY Deneka, Y Baca, IG Serebriiskii, E Nicolas… - Clinical Cancer …, 2022 - AACR
Purpose: Head and neck squamous cell carcinoma (HNSCC) is a frequently devastating
cancer that affects more than a half million people annually worldwide. Although some …

A novel tumor mutational burden-based risk model predicts prognosis and correlates with immune infiltration in ovarian cancer

H Wang, J Liu, J Yang, Z Wang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Tumor mutational burden (TMB) has been reported to determine the response to
immunotherapy, thus affecting the patient's prognosis in many cancers. However, it is …

[HTML][HTML] Prognostic and immunological role of CD36: A pan-cancer analysis

YJ Chen, WX Liao, SZ Huang, YF Yu, JY Wen… - Journal of …, 2021 - ncbi.nlm.nih.gov
CD36 plays a critical role in lipid metabolism, which is closely associated with human
immunity. However, the role of CD36 in cancer remains unclear. We performed a pan …

Relationship between tumor mutational burden, PD-L1, patient characteristics, and response to immune checkpoint inhibitors in head and neck squamous cell …

KM Burcher, JW Lantz, E Gavrila, A Abreu, JT Burcher… - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy has prompted a dramatic change in the management of
head and neck squamous cell carcinoma (HNSCC), but the percentage of patients …

Pan-Cancer Molecular Characterization of m6A Regulators and Immunogenomic Perspective on the Tumor Microenvironment

J Zhu, J Xiao, M Wang, D Hu - Frontiers in Oncology, 2021 - frontiersin.org
Purpose N6-methyladenosine (m6A) methylation plays a critical role in diverse biological
processes. However, knowledge regarding the constitution of m6A on tumor …

The application of next-generation sequencing to define factors related to oral cancer and discover novel biomarkers

S Kim, JW Lee, YS Park - Life, 2020 - mdpi.com
Despite the introduction of next-generation sequencing in the realm of DNA sequencing
technology, it is not often used in the investigation of oral squamous cell carcinoma (OSCC) …

Comprehensive genomic profiling reveals clinical associations in response to immune therapy in head and neck cancer

R Noji, K Tohyama, T Kugimoto, T Kuroshima, H Hirai… - Cancers, 2022 - mdpi.com
Simple Summary The response rate of head and neck cancer (HNC) to immune checkpoint
inhibitors (ICIs) can be as low as 20%. Biomarkers need to be elucidated to predict …

Comprehensive analysis of tumor immune microenvironment characteristics for the prognostic prediction and immunotherapy of oral squamous cell carcinoma

Y Zhao, D Chen, J Yin, J Xie, C Sun, M Lu - Frontiers in Genetics, 2022 - frontiersin.org
Background: Oral squamous cell carcinoma (OSCC) is the most common cancer of oral and
maxillofacial region. A recent clinical research has shown that tumor immune …