Burden of liver diseases in the world

SK Asrani, H Devarbhavi, J Eaton, PS Kamath - Journal of hepatology, 2019 - Elsevier
Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …

Hepatic encephalopathy

EFM Wijdicks - New England Journal of Medicine, 2016 - Mass Medical Soc
Hepatic Encephalopathy | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

ESPEN guideline on clinical nutrition in liver disease

M Plauth, W Bernal, S Dasarathy, M Merli, LD Plank… - Clinical nutrition, 2019 - Elsevier
This update of evidence-based guidelines (GL) aims to translate current evidence and
expert opinion into recommendations for multidisciplinary teams responsible for the optimal …

EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure

J Wendon, J Cordoba, A Dhawan, FS Larsen… - Journal of …, 2017 - Elsevier
The term acute liver failure (ALF) is frequently applied as a generic expression to describe
patients presenting with or developing an acute episode of liver dysfunction. In the context of …

Molecular pathophysiology of cerebral edema

JA Stokum, V Gerzanich… - Journal of Cerebral Blood …, 2016 - journals.sagepub.com
Advancements in molecular biology have led to a greater understanding of the individual
proteins responsible for generating cerebral edema. In large part, the study of cerebral …

Protective effects of microbiome-derived inosine on lipopolysaccharide-induced acute liver damage and inflammation in mice via mediating the TLR4/NF-κB pathway

W Guo, Q Xiang, B Mao, X Tang, S Cui… - Journal of agricultural …, 2021 - ACS Publications
This research assessed the anti-inflammatory and hepatoprotective properties of inosine
and the associated mechanism. Inosine pretreatment significantly reduced the secretion of …

Acute liver failure

W Bernal, J Wendon - New England Journal of Medicine, 2013 - Mass Medical Soc
Acute Liver Failure | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …

Addressing liver disease in the UK: a blueprint for attaining excellence in health care and reducing premature mortality from lifestyle issues of excess consumption of …

R Williams, R Aspinall, M Bellis, G Camps-Walsh… - The Lancet, 2014 - thelancet.com
Executive summary Liver disease in the UK stands out as the one glaring exception to the
vast improvements made during the past 30 years in health and life expectancy for chronic …

Acute-on-chronic liver failure: terminology, mechanisms and management

SK Sarin, A Choudhury - Nature Reviews Gastroenterology & …, 2016 - nature.com
Acute-on-chronic liver failure (ACLF) is a distinct clinical entity and differs from acute liver
failure and decompensated cirrhosis in timing, presence of acute precipitant, course of …

Outcomes in adults with acute liver failure between 1998 and 2013: an observational cohort study

A Reuben, H Tillman, RJ Fontana, T Davern… - Annals of internal …, 2016 - acpjournals.org
Background: Acute liver failure (ALF) is a rare syndrome of severe, rapid-onset hepatic
dysfunction—without prior advanced liver disease—that is associated with high morbidity …