Computational modeling of realistic cell membranes
Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
[HTML][HTML] Perspective on the Martini model
SJ Marrink, DP Tieleman - Chemical Society Reviews, 2013 - pubs.rsc.org
The Martini model, a coarse-grained force field for biomolecular simulations, has found a
broad range of applications since its release a decade ago. Based on a building block …
broad range of applications since its release a decade ago. Based on a building block …
[HTML][HTML] Anomalous diffusion models and their properties: non-stationarity, non-ergodicity, and ageing at the centenary of single particle tracking
Modern microscopic techniques following the stochastic motion of labelled tracer particles
have uncovered significant deviations from the laws of Brownian motion in a variety of …
have uncovered significant deviations from the laws of Brownian motion in a variety of …
Characterization of lipid–protein interactions and lipid-mediated modulation of membrane protein function through molecular simulation
The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …
cell, where key processes such as selective transport of material and exchange of …
Protein crowding in lipid bilayers gives rise to non-Gaussian anomalous lateral diffusion of phospholipids and proteins
Biomembranes are exceptionally crowded with proteins with typical protein-to-lipid ratios
being around 1∶ 50− 1∶ 100. Protein crowding has a decisive role in lateral membrane …
being around 1∶ 50− 1∶ 100. Protein crowding has a decisive role in lateral membrane …
Manipulation and motion of organelles and single molecules in living cells
K Norregaard, R Metzler, CM Ritter… - Chemical …, 2017 - ACS Publications
The biomolecule is among the most important building blocks of biological systems, and a
full understanding of its function forms the scaffold for describing the mechanisms of higher …
full understanding of its function forms the scaffold for describing the mechanisms of higher …
[HTML][HTML] Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …
[HTML][HTML] Non-Brownian diffusion in lipid membranes: Experiments and simulations
The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …
connection to the binding of various particles and macromolecules to the membrane—are …
Anomalous diffusion, aging, and nonergodicity of scaled Brownian motion with fractional Gaussian noise: Overview of related experimental observations and models
How does a systematic time-dependence of the diffusion coefficient D (t) affect the ergodic
and statistical characteristics of fractional Brownian motion (FBM)? Here, we answer this …
and statistical characteristics of fractional Brownian motion (FBM)? Here, we answer this …
[HTML][HTML] Excessive aggregation of membrane proteins in the Martini model
M Javanainen, H Martinez-Seara, I Vattulainen - PloS one, 2017 - journals.plos.org
The coarse-grained Martini model is employed extensively to study membrane protein
oligomerization. While this approach is exceptionally promising given its computational …
oligomerization. While this approach is exceptionally promising given its computational …