Transport mechanisms at the malaria parasite-host cell interface
Obligate intracellular malaria parasites reside within a vacuolar compartment generated
during invasion which is the principal interface between pathogen and host. To subvert their …
during invasion which is the principal interface between pathogen and host. To subvert their …
Advances in understanding red blood cell modifications by Babesia
H Hakimi, J Yamagishi, S Kawazu, M Asada - PLoS Pathogens, 2022 - journals.plos.org
Babesia are tick-borne protozoan parasites that can infect livestock, pets, wildlife animals,
and humans. In the mammalian host, they invade and multiply within red blood cells (RBCs) …
and humans. In the mammalian host, they invade and multiply within red blood cells (RBCs) …
Chromosome-level genome assembly of Babesia caballi reveals diversity of multigene families among Babesia species
A Ochi, T Kidaka, H Hakimi, M Asada, J Yamagishi - BMC genomics, 2023 - Springer
Background Babesia caballi is an intraerythrocytic parasite from the phylum Apicomplexa,
capable of infecting equids and causing equine piroplasmosis. However, since there is …
capable of infecting equids and causing equine piroplasmosis. However, since there is …
Comparative single-cell transcriptional atlases of Babesia species reveal conserved and species-specific expression profiles
Babesia is a genus of apicomplexan parasites that infect red blood cells in vertebrate hosts.
Pathology occurs during rapid replication cycles in the asexual blood stage of infection …
Pathology occurs during rapid replication cycles in the asexual blood stage of infection …
Promises and pitfalls of parasite patch-clamp
Protozoan parasites acquire essential ions, nutrients, and other solutes from their insect and
vertebrate hosts by transmembrane uptake. For intracellular stages, these solutes must …
vertebrate hosts by transmembrane uptake. For intracellular stages, these solutes must …
Critical role of Babesia bovis spherical body protein 3 in ridge formation on infected red blood cells
A Fathi, H Hakimi, M Sakaguchi, J Yamagishi… - PLoS …, 2024 - journals.plos.org
Babesia bovis, an apicomplexan intraerythrocytic protozoan parasite, causes serious
economic loss to cattle industries around the world. Infection with this parasite leads to …
economic loss to cattle industries around the world. Infection with this parasite leads to …
Plasmepsin-like Aspartyl Proteases in Babesia
P Šnebergerová, P Bartošová-Sojková, M Jalovecká… - Pathogens, 2021 - mdpi.com
Apicomplexan genomes encode multiple pepsin-family aspartyl proteases (APs) that
phylogenetically cluster to six independent clades (A to F). Such diversification has been …
phylogenetically cluster to six independent clades (A to F). Such diversification has been …
Recent Advances in Molecular Genetic Tools for Babesia
H Hakimi, M Asada, S Kawazu - Veterinary Sciences, 2021 - mdpi.com
Development of in vitro culture and completion of genome sequencing of several Babesia
parasites promoted the efforts to establish transfection systems for these parasites to dissect …
parasites promoted the efforts to establish transfection systems for these parasites to dissect …
Isolation of viable Babesia bovis merozoites to study parasite invasion
H Hakimi, M Asada, T Ishizaki, S Kawazu - Scientific reports, 2021 - nature.com
Babesia parasite invades exclusively red blood cell (RBC) in mammalian host and induces
alterations to host cell for survival. Despite the importance of Babesia in livestock industry …
alterations to host cell for survival. Despite the importance of Babesia in livestock industry …
Whole genome sequence and diversity in multigene families of Babesia ovis
J Yamagishi, O Ceylan, X Xuan… - Frontiers in Cellular and …, 2023 - frontiersin.org
Ovine babesiosis, caused by Babesia ovis, is an acute, lethal, and endemic disease
worldwide and causes a huge economic loss to animal industry. Pathogen genome …
worldwide and causes a huge economic loss to animal industry. Pathogen genome …