Ovarian cancer is the second most common cause of gynecologic cancer death in women
around the world. The outcomes are complicated, because the disease is often diagnosed …

Abstract Endometrial cancer accounts for~ 76,000 deaths among women each year
worldwide. Disease mortality and the increasing number of new diagnoses make …

Endometriosis is characterized by ectopic endometrial-like epithelium and stroma, of which
molecular characteristics remain to be fully elucidated. We sequenced 107 ovarian …

PTEN is a phosphatase which metabolises PIP 3, the lipid product of PI 3-Kinase, directly
opposing the activation of the oncogenic PI3K/AKT/mTOR signalling network. Accordingly …

TP53 mutations are ubiquitous in high‐grade serous ovarian carcinomas (HGSOC), and the
presence of TP53 mutation discriminates between high and low‐grade serous carcinomas …

The human body consists of countless cells with the possibility of excessive and
uncontrolled proliferation under certain dysregulated circumstances that could cause …

Epithelial ovarian cancer is the second commonest cause of death amongst all
gynaecological cancers. Treatment is challenging because almost 75% of cases are …

Background Epithelial ovarian cancer (OC) is a heterogenous disease consisting of five
major histologically distinct subtypes: high-grade serous (HGSOC), low-grade serous …

Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

Abstract Development of novel strategies to overcome chemoresistance is central goal in
ovarian cancer research. Natural history of the cancer development and progression is …