How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective Neisseria meningitidis Vaccines

R Gasparini, D Panatto, NL Bragazzi… - Journal of …, 2015 - Wiley Online Library
In the last decades, tremendous advancement in dissecting the mechanisms of
pathogenicity of Neisseria meningitidis at a molecular level has been achieved, exploiting …

A deeper mining on the protein composition of VA-MENGOC-BC®: An OMV-based vaccine against N. meningitidis serogroup B and C

Y Masforrol, J Gil, D Garcia, J Noda… - Human Vaccines & …, 2017 - Taylor & Francis
The protein composition of an Outer Membrane Vesicle (OMV) preparation that constitutes
the active pharmaceutical ingredient of VA-MENGOC-BC®, an effective vaccine against …

[HTML][HTML] Designing of Complex Multi-epitope Peptide Vaccine Based on Omps of Klebsiella pneumoniae: An In Silico Approach

T Farhadi, N Nezafat, Y Ghasemi, Z Karimi… - International Journal of …, 2015 - Springer
Klebsiella pneumoniae is a hospital-acquired pathogen that leads to various infections.
There is a great interest in developing an efficient Klebsiella vaccine and epitope-based …

Rational design of multimeric based subunit vaccine against Mycoplasma pneumonia: Subtractive proteomics with immunoinformatics framework

M Mahmood, A Javaid, F Shahid, UA Ashfaq - Infection, Genetics and …, 2021 - Elsevier
Mycoplasma pneumoniae is the prevalent cause of acquired respiratory infections around
the globe. A multi-epitope vaccine (MEV) must be developed to combat infections of M …

Improved Proteomic Approach for the Discovery of Potential Vaccine Targets in Trypanosoma cruzi

ES Nakayasu, TJP Sobreira, R Torres… - Journal of proteome …, 2012 - ACS Publications
Chagas disease, caused by Trypanosoma cruzi, is a devastating parasitic infection affecting
millions of people. Although many efforts have been made for the development of …

Combining DNA Vaccine and AIDA-1 in Attenuated Salmonella Activates Tumor-Specific CD4+ and CD8+ T-cell Responses

Y Mei, L Zhao, Y Liu, H Gong, Y Song, L Lei… - Cancer immunology …, 2017 - AACR
Stimulation of tumor-specific responses in both CD4+ and CD8+ T cells has been a
challenge for effective tumor vaccines. We designed a vaccine vector containing the AIDA-1 …

Systemic immunization with an epitope-based vaccine elicits a Th1-biased response and provides protection against Helicobacter pylori in mice

HB Li, JY Zhang, YF He, L Chen, B Li, KY Liu… - Vaccine, 2012 - Elsevier
Vaccine-mediated Th1-biased CD4+ T cell responses have been shown to be crucial for
protection against Helicobacter pylori (H. pylori). In this study, we investigated whether a …

[HTML][HTML] Genome-wide scan for potential CD4+ T-cell vaccine candidates in Candida auris by exploiting reverse vaccinology and evolutionary information

SK Gupta, Ö Osmanoglu, R Minocha, SR Bandi… - Frontiers in …, 2022 - frontiersin.org
Candida auris is a globally emerging fungal pathogen responsible for causing nosocomial
outbreaks in healthcare associated settings. It is known to cause infection in all age groups …

Protection against Helicobacter pylori infection in BALB/c mice by oral administration of multi-epitope vaccine of CTB-UreI-UreB

J Yang, L Dai, X Pan, H Wang, B Li, J Zhu… - Pathogens and …, 2015 - academic.oup.com
Chronic gastric infection by the Gram-negative bacterium Helicobacter pylori (H. pylori) is
strongly associated with gastritis, gastric ulcer and the development of distal gastric …

[HTML][HTML] Immunisation With Immunodominant Linear B Cell Epitopes Vaccine of Manganese Transport Protein C Confers Protection against Staphylococcus aureus …

HJ Yang, JY Zhang, C Wei, LY Yang, QF Zuo… - PLoS …, 2016 - journals.plos.org
Vaccination strategies for Staphylococcus aureus, particularly methicillin-resistant S. aureus
(MRSA) infections have attracted much research attention. Recent efforts have been made …