Voltage-dependent Ca2+ channels (Cavs) are indispensable for coupling action potentials
with Ca2+ signaling in living organisms. The structure of Cavs is similar to that of voltage …

Batrachotoxin (BTX), an alkaloid from skin secretions of dendrobatid frogs, causes paralysis
and death by facilitating activation and inhibiting deactivation of eukaryotic voltage-gated …

Voltage‐gated sodium channels are crucial for electro‐signalling in living systems. Analysis
of the molecular mechanism requires both fine electrophysiological evaluation and high …

Background: Anticonvulsants are drugs used in the treatment of seizures; their
pharmacology includes promoters of brain inhibition and inhibitors of brain activity. Of the …

Abstract Voltage-dependent Ca 2+ channels (Cavs) are indispensable for coupling action
potentials with Ca 2+ signaling in living organisms. The structure of Cavs is similar to that of …

Lokalanästhetika unterbrechen via Blockade von Natriumkanälen die Fortleitung von
Aktionspotentialen entlang neuronaler Strukturen.[1] Wie Lokalanästhetika an ihren Effektort …

Slow inactivation in voltage-gated sodium channels (NaV) directly regulates the excitability
of neurons, cardiac myocytes, and skeletal muscles. Although NaV slow inactivation …