The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

mRNA vaccines for COVID-19 and diverse diseases

A Hussain, H Yang, M Zhang, Q Liu, G Alotaibi… - Journal of Controlled …, 2022 - Elsevier
Since its outbreak in late 2019, the novel coronavirus disease 2019 (COVID-19) has spread
to every continent on the planet. The global pandemic has affected human health and …

An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines

F Bayani, NS Hashkavaei, S Arjmand, S Rezaei… - Progress in Biophysics …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that
has caused the recent coronavirus disease (COVID-19) global pandemic. The current …

COVID-19 vaccination and the rate of immune and autoimmune adverse events following immunization: insights from a narrative literature review

N Mahroum, N Lavine, A Ohayon, R Seida… - Frontiers in …, 2022 - frontiersin.org
Despite their proven efficacy and huge contribution to the health of humankind, vaccines
continue to be a source of concern for some individuals around the world. Vaccinations …

Advances of reverse vaccinology for mRNA vaccine design against SARS-CoV-2: a review of methods and tools

MK da Silva, DMO Campos, S Akash, S Akter, LC Yee… - Viruses, 2023 - mdpi.com
mRNA vaccines are a new class of vaccine that can induce potent and specific immune
responses against various pathogens. However, the design of mRNA vaccines requires the …

Universal flu mRNA vaccine: Promises, prospects, and problems

AA Deviatkin, RA Simonov, KA Trutneva, AA Maznina… - Vaccines, 2022 - mdpi.com
The seasonal flu vaccine is, essentially, the only known way to prevent influenza epidemics.
However, this approach has limited efficacy due to the high diversity of influenza viruses …

[HTML][HTML] The Safety and Effectiveness of mRNA Vaccines Against SARS-CoV-2

YF Jamous, DA Alhomoud - Cureus, 2023 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in numerous deaths …

In vitro transcribed RNA-based platform vaccines: past, present, and future

AD Perenkov, AD Sergeeva, MV Vedunova, DV Krysko - Vaccines, 2023 - mdpi.com
mRNA was discovered in 1961, but it was not used as a vaccine until after three decades.
Recently, the development of mRNA vaccine technology gained great impetus from the …

[PDF][PDF] New Perspectives on Reverse Translation: Brief History and Updates

A Wicaksono, VD Kharisma… - Universitas …, 2023 - revistas.javeriana.edu.co
Since the 1950s, reverse translation has been an enigmatic part of Crick's central dogma of
molecular biology. It might be described as the possibility to back-translate information from …

Recent advances in mRNA‐based vaccine for cancer therapy; bench to bedside

HA Kenoosh, H Pallathadka, A Hjazi… - Cell Biochemistry …, 2024 - Wiley Online Library
The messenger RNA (mRNA) vaccines have progressed from a theoretical concept to a
clinical reality over the last few decades. Compared to conventional vaccination methods …