Role of biomaterials and controlled architecture on tendon/ligament repair and regeneration

YJ No, M Castilho, Y Ramaswamy… - Advanced …, 2020 - Wiley Online Library
Engineering synthetic scaffolds to repair and regenerate ruptured native tendon and
ligament (T/L) tissues is a significant engineering challenge due to the need to satisfy both …

Fibrous systems as potential solutions for tendon and ligament repair, healing, and regeneration

C Rinoldi, E Kijeńska‐Gawrońska… - Advanced …, 2021 - Wiley Online Library
Tendon and ligament injuries caused by trauma and degenerative diseases are frequent
and affect diverse groups of the population. Such injuries reduce musculoskeletal …

Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering

SB Orr, A Chainani, KJ Hippensteel, A Kishan… - Acta biomaterialia, 2015 - Elsevier
The rotator cuff consists of several tendons and muscles that provide stability and force
transmission in the shoulder joint. Whereas most rotator cuff tears are amenable to suture …

The biodegradable spacer as a novel treatment modality for massive rotator cuff tears: a prospective study with 5-year follow-up

V Senekovic, B Poberaj, L Kovacic, M Mikek… - Archives of orthopaedic …, 2017 - Springer
Background The management of massive, irreparable rotator cuff tears (RCT) is challenging
and associated with high failure rates. There are no current consensus or definitive …

Fiber-reinforced tough hydrogels

WRK Illeperuma, JY Sun, Z Suo, JJ Vlassak - Extreme Mechanics Letters, 2014 - Elsevier
Using strong fibers to reinforce a hydrogel is highly desirable but difficult. Such a composite
would combine the attributes of a solid that provides strength and a liquid that transports …

Multilayered electrospun scaffolds for tendon tissue engineering

A Chainani, KJ Hippensteel, A Kishan… - … Engineering Part A, 2013 - liebertpub.com
Full-thickness rotator cuff tears are one of the most common causes of shoulder pain in
people over the age of 65. High retear rates and poor functional outcomes are common after …

Decellularized xenografts in regenerative medicine: From processing to clinical application

H Capella‐Monsonís, DI Zeugolis - Xenotransplantation, 2021 - Wiley Online Library
Decellularized xenografts are an inherent component of regenerative medicine. Their
preserved structure, mechanical integrity and biofunctional composition have well …

A collagen/PLA hybrid scaffold supports tendon‐derived cell growth for tendon repair and regeneration

Y Xie, F Zhang, O Akkus… - Journal of Biomedical …, 2022 - Wiley Online Library
A rotator cuff tendon tear is a common shoulder injury with a relatively high rate of
recurrence after surgical repair. In order to reinforce the repair and reduce the risk of clinical …

[HTML][HTML] Clinical perspectives for repairing rotator cuff injuries with multi-tissue regenerative approaches

X Zhang, D Wang, Z Wang, SK Ling, PS Yung… - Journal of Orthopaedic …, 2022 - Elsevier
Background In the musculoskeletal system, bone, tendon, and muscle form highly integrated
multi-tissue units such as the rotator cuff complex, which facilitates functional and dynamic …

Functionally graded, bone‐and tendon‐like polyurethane for rotator cuff repair

DFE Ker, D Wang, AW Behn, ETH Wang… - Advanced functional …, 2018 - Wiley Online Library
Critical considerations in engineering biomaterials for rotator cuff repair include bone‐
tendon‐like mechanical properties to support physiological loading and biophysicochemical …