Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions

G Li, Y Hu, W Zhang, J Wang, W Ji, P Manza… - Molecular …, 2023 - nature.com
Obesity has tripled over the past 40 years to become a major public health issue, as it is
linked with increased mortality and elevated risk for various physical and neuropsychiatric …

A systematic review of resting-state functional connectivity in obesity: Refining current neurobiological frameworks and methodological considerations moving forward

N Parsons, T Steward, R Clohesy, H Almgren… - Reviews in Endocrine …, 2022 - Springer
Obesity is the second most common cause of preventable morbidity worldwide. Resting-
state functional magnetic resonance imaging (fMRI) has been used extensively to …

Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals

S Ravichandran, RR Bhatt, B Pandit, V Osadchiy… - Scientific reports, 2021 - nature.com
Functional neuroimaging studies in obesity have identified alterations in the connectivity
within the reward network leading to decreased homeostatic control of ingestive behavior …

Metabolism-related brain morphology accelerates aging and predicts neurodegenerative diseases and stroke: a UK Biobank study

C Shen, C Liu, A Qiu - Translational Psychiatry, 2023 - nature.com
Abstracts Metabolic syndrome (MetS) is characterized by a constellation of metabolic risk
factors, including obesity, hypertriglyceridemia, low high-density lipoprotein (HDL) levels …

[HTML][HTML] Hypothalamic integrity is necessary for sustained weight loss after bariatric surgery: A prospective, cross-sectional study

U Dischinger, L Kötzner, P Kovatcheva-Datchary… - Metabolism, 2023 - Elsevier
Objective The hypothalamus is the main integrator of peripheral and central signals in the
control of energy homeostasis. Its functional relevance for the effectivity of bariatric surgery is …

Higher body mass index is associated with reduced posterior default mode connectivity in older adults

F Beyer, S Kharabian Masouleh… - Human brain …, 2017 - Wiley Online Library
Obesity is a complex neurobehavioral disorder that has been linked to changes in brain
structure and function. However, the impact of obesity on functional connectivity and …

[HTML][HTML] Top-down control of conditioned overconsumption is mediated by insular cortex Nos1 neurons

SA Stern, EP Azevedo, LE Pomeranz, KR Doerig… - Cell Metabolism, 2021 - cell.com
Associative learning allows animals to adapt their behavior in response to environmental
cues. For example, sensory cues associated with food availability can trigger …

[HTML][HTML] Integration of homeostatic signaling and food reward processing in the human brain

JJ Simon, A Wetzel, MH Sinno, M Skunde… - JCI insight, 2017 - ncbi.nlm.nih.gov
BACKGROUND. Food intake is guided by homeostatic needs and by the reward value of
food, yet the exact relation between the two remains unclear. The aim of this study was to …

Resting-state functional changes in the precuneus within first-episode drug-naive patients with MDD

G Li, K Rossbach, A Zhang, P Liu… - … disease and treatment, 2018 - Taylor & Francis
Background Major depressive disorder (MDD) is a leading psychiatric disorder that has a
lack of biomarkers for a diagnosis. Purpose The objective of this study was to examine the …

Oxytocin reduces the functional connectivity between brain regions involved in eating behavior in men with overweight and obesity

L Kerem, N Hadjikhani, L Holsen, EA Lawson… - International Journal of …, 2020 - nature.com
Background Oxytocin (OXT), shown to decrease food intake in animal models and men, is a
promising novel treatment for obesity. We have shown that in men with overweight and …