The evolution of macrophages has made them primordial for both development and
immunity. Their functions range from the shaping of body plans to the ingestion and …

Actinobacteria constitute one of the largest phyla among Bacteria and represent gram-
positive bacteria with a high G+ C content in their DNA. This bacterial group includes …

Covering: up to 2013 Although holo-acyl carrier protein synthase, AcpS, a
phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until …

Simple Summary Recently, there has been a considerable rise in infections caused by
nontuberculous mycobacteria (NTM). These mycobacteria, which comprise a large and …

Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of
Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of …

Introduction The neglected tropical diseases (NTDs) are infectious diseases that principally
impact the world's poorest people. They have been neglected for decades, initially as part of …

Buruli ulcer is a neglected emerging disease that has recently been reported in some
countries as the second most frequent mycobacterial disease in humans after tuberculosis …

Pulmonary tuberculosis, a disease caused by Mycobacterium tuberculosis (Mtb), manifests
with a persistent cough as both a primary symptom and mechanism of transmission. The …

▪ Abstract Pathogenic mycobacteria, including the causative agents of tuberculosis and
leprosy, are responsible for considerable morbidity and mortality worldwide. A hallmark of …

Mycobacteria use type VII secretion (T7S) systems to secrete proteins across their complex
cell envelope. Pathogenic mycobacteria, such as the notorious pathogen Mycobacterium …