II. Nuclear Receptors: General Concepts A. Anatomy of nuclear receptors B. Mechanisms of
action III. Orphan Nuclear Receptors A. Definition

▪ Abstract This review provides a synthesis that combines data from classical
experimentation and recent advances in our understanding of early eye development …

Several eye-field transcription factors (EFTFs) are expressed in the anterior region of the
vertebrate neural plate and are essential for eye formation. The Xenopus EFTFs ET, Rx1 …

Cranial placodes are focal regions of thickened ectoderm in the head of vertebrate embryos
that give rise to a wide variety of cell types, including elements of the paired sense organs …

Over the last twenty years, there has been rapid growth of a new approach to understanding
the evolution of organismic form. This evolutionary developmental biology, or 'evo-devo', is …

This chapter provides an overview of the early developmental origins of six ocular tissues:
the cornea, lens, ciliary body, iris, neural retina, and retina pigment epithelium. Many of …

Neuroendocrine control mechanisms are observed in all animals that possess a nervous
system. Recent analyses of neuroendocrine functions in invertebrate model systems reveal …

Unusual neuro-ophthalmologic symptoms and signs that go unexplained should warrant a
thorough investigation for paraneoplastic syndromes. Although these syndromes are rare …

The novel homeobox-containing gene Vax1, a member of the Emx/Not gene family, is
specifically expressed in the developing basal forebrain and optic nerve. Here, we show that …

Nuclear receptors comprise a large and expanding family of transcription factors involved in
diverse aspects of animal physiology and development, the functions of which can be …