Having a hypoxic microenvironment is a common and salient feature of most solid tumors.
Hypoxia has a profound effect on the biological behavior and malignant phenotype of …

Epithelial tissues line the outer surfaces of the mammalian body and protect from external
harm. In skin, the epithelium is maintained by distinct stem cell populations residing in the …

Chronic hard-to-heal wounds draw great attention worldwide, as their treatments are limited
by infections and hypoxia. Inspired by the natural oxygen production capacity of algae and …

Tissue repair processes maintain proper organ function following mechanical or infection-
related damage. In addition to antibacterial properties, mucosal associated invariant T …

Whereas the cellular and molecular features of human inflammatory skin diseases are well
characterized, their tissue context and systemic impact remain poorly understood. We thus …

Epithelial cells that participated in wound repair elicit a more efficient response to future
injuries, which is believed to be locally restricted. Here we show that cell adaptation …

Photodynamic therapy (PDT) acts as a powerful weapon against infectious diseases for its
enormous antimicrobial activity that quickly elicits storms of reactive oxygen species (ROS) …

Angiogenesis, the growth of new blood vessels from pre-existing vessels, occurs during
development, injury repair, and tumorigenesis to deliver oxygen, immune cells, and nutrients …

The epithelial tissues that line our body, such as the skin and gut, have remarkable
regenerative prowess and continually renew throughout our lifetimes. Owing to their barrier …

During ontogeny, γδ T cells emerge from the thymus and directly seed peripheral tissues for
in situ immunity. However, their functional role in humans has largely been defined from …