[HTML][HTML] Pathogenesis of osteoarthritis: risk factors, regulatory pathways in chondrocytes, and experimental models

Y He, Z Li, PG Alexander, BD Ocasio-Nieves, L Yocum… - Biology, 2020 - mdpi.com
As the most common chronic degenerative joint disease, osteoarthritis (OA) is the leading
cause of pain and physical disability, affecting millions of people worldwide. Mainly …

[HTML][HTML] Osteoarthritis: toward a comprehensive understanding of pathological mechanism

DI Chen, J Shen, W Zhao, T Wang, L Han, JL Hamilton… - Bone research, 2017 - nature.com
Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of
pain and disability in adult individuals. The etiology of OA includes joint injury, obesity …

Ageing and osteoarthritis

PK Sacitharan - Biochemistry and cell biology of ageing: part II clinical …, 2019 - Springer
The increase in global lifespan has in turn increased the prevalence of osteoarthritis which
is now the most common type of arthritis. Cartilage tissue located on articular joints erodes …

Epidemiology of osteoarthritis

Y Zhang, JM Jordan - Clinics in geriatric medicine, 2010 - geriatric.theclinics.com
Osteoarthritis (OA) is the most common joint disorder in the United States. 1 Among adults
60 years of age or older the prevalence of symptomatic knee OA is approximately 10% in …

Knee osteoarthritis: a review of management options

SM Hussain, DW Neilly, S Baliga… - Scottish medical …, 2016 - journals.sagepub.com
Osteoarthritis of the knee is a complex peripheral joint disorder with multiple risk factors. The
molecular basis of osteoarthritis has been generally accepted; however, the exact …

[HTML][HTML] Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes

G Li, J Yin, J Gao, TS Cheng, NJ Pavlos… - Arthritis research & …, 2013 - Springer
Osteoarthritis (OA) is a major cause of disability in the adult population. As a progressive
degenerative joint disorder, OA is characterized by cartilage damage, changes in the …

[HTML][HTML] The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee

JWP Michael, KU Schlüter-Brust… - Deutsches Arzteblatt …, 2010 - ncbi.nlm.nih.gov
Background Osteoarthritis is the most common joint disease of adults worldwide. Its
incidence rises with age. Both intrinsic and extrinsic risk factors promote its development. In …

[HTML][HTML] Mechanisms of osteoarthritic pain. Studies in humans and experimental models

A Eitner, GO Hofmann, HG Schaible - Frontiers in molecular …, 2017 - frontiersin.org
Pain due to osteoarthritis (OA) is one of the most frequent causes of chronic pain. However,
the mechanisms of OA pain are poorly understood. This review addresses the mechanisms …

Osteoarthritis: new insights. Part 1: the disease and its risk factors

DT Felson, RC Lawrence, PA Dieppe… - Annals of internal …, 2000 - acpjournals.org
Osteoarthritis is the most common form of arthritis, affecting millions of people in the United
States. It is a complex disease whose etiology bridges biomechanics and biochemistry …

Epidemiology of osteoarthritis

T Neogi, Y Zhang - Rheumatic Disease Clinics, 2013 - rheumatic.theclinics.com
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