Recent advancement, immune responses, and mechanism of action of various vaccines against intracellular bacterial infections
Emerging and re-emerging bacterial infections are a serious threat to human and animal
health. Extracellular bacteria are free-living, while facultative intracellular bacteria replicate …
health. Extracellular bacteria are free-living, while facultative intracellular bacteria replicate …
Programmed cell death in the evolutionary race against bacterial virulence factors
CA Lacey, EA Miao - Cold Spring Harbor perspectives in …, 2020 - cshperspectives.cshlp.org
Innate immune sensors can recognize when host cells are irrevocably compromised by
pathogens, and in response can trigger programmed cell death (pyroptosis, apoptosis, and …
pathogens, and in response can trigger programmed cell death (pyroptosis, apoptosis, and …
Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation
Enzymes from pathogens often modulate host protein post-translational modifications
(PTMs), facilitating survival and proliferation of pathogens. Shigella virulence factors IpaJ …
(PTMs), facilitating survival and proliferation of pathogens. Shigella virulence factors IpaJ …
Shigella outer membrane vesicles as promising targets for vaccination
M Qasim, M Wrage, B Nüse, J Mattner - International Journal of Molecular …, 2022 - mdpi.com
The clinical symptoms of shigellosis, a gastrointestinal infection caused by Shigella spp.
range from watery diarrhea to fulminant dysentery. Endemic infections, particularly among …
range from watery diarrhea to fulminant dysentery. Endemic infections, particularly among …
Identification and evaluation of novel vaccine candidates against Shigella flexneri through reverse vaccinology approach
A Hajialibeigi, J Amani, SLM Gargari - Applied Microbiology and …, 2021 - Springer
Shigellosis is a significant type of diarrhea that causes 160,000 deaths annually in a global
scale. The mortality occurs mainly in children less than 5 years of age. No licensed vaccine …
scale. The mortality occurs mainly in children less than 5 years of age. No licensed vaccine …
Expression and purification of TolC as a recombinant protein vaccine against Shigella flexneri and evaluation of immunogenic response in mice
Background Shigella is one of the major causes of dysenteric diarrhea, which is known
shigelosis. Shigelosis causes 160,000 deaths annually of diarrheal disease in the global …
shigelosis. Shigelosis causes 160,000 deaths annually of diarrheal disease in the global …
Exopolysaccharide secreted by Lactiplantibacillus plantarum Y12 showed inhibitory effect on the pathogenicity of Shigella flexneri in vitro and in vivo
Y Song, M Sun, G Mu, Y Tuo - International Journal of Biological …, 2024 - Elsevier
Shigella flexneri is a prevalent foodborne and waterborne pathogen that threatens human
health. Our previous research indicated that the Lactiplantibacillus plantarum Y12 …
health. Our previous research indicated that the Lactiplantibacillus plantarum Y12 …
[PDF][PDF] Evaluation of anti-biofilm, anti-quorum, anti-dysenteric potential of designed polyherbal formulation: in vitro and in vivo study.
Bacillary dysentery (shigellosis) continues to cause havoc worldwide, with a high infectivity
rate. It causes bloody diarrhea, and around 99% of bacillary dysentery cases occur in …
rate. It causes bloody diarrhea, and around 99% of bacillary dysentery cases occur in …
[HTML][HTML] An in vivo acute toxicity and anti-shigellosis effect of designed formulation on rat
Introduction Shigellosis is an intestinal disease and is one of the main causes of morbidity
and mortality among children in India. The study aims to analyze the effect of the designed …
and mortality among children in India. The study aims to analyze the effect of the designed …
Azithromycin alters Colony Stimulating Factor-1R (CSF-1R) expression and functional output of murine bone marrow-derived macrophages: A novel report
Antibiotic treatment may lead to side effects that require mechanistic explanation. We
investigated the effect of azithromycin (AZM) treatment on bone marrow-derived …
investigated the effect of azithromycin (AZM) treatment on bone marrow-derived …