Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms
YQ He, CC Zhou, LY Yu, L Wang, J Deng… - Pharmacological …, 2021 - Elsevier
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
Advances in the use of exosomes for the treatment of ALI/ARDS
C Liu, K Xiao, L Xie - Frontiers in Immunology, 2022 - frontiersin.org
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a critical clinical
syndrome with high morbidity and mortality. Currently, the primary treatment for ALI/ARDS is …
syndrome with high morbidity and mortality. Currently, the primary treatment for ALI/ARDS is …
Progress in preclinical studies of macrophage autophagy in the regulation of ALI/ARDS
C Liu, K Xiao, L Xie - Frontiers in immunology, 2022 - frontiersin.org
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a critical clinical
syndrome with high morbidity and mortality that poses a major challenge in critical care …
syndrome with high morbidity and mortality that poses a major challenge in critical care …
Human umbilical cord mesenchymal stromal cell small extracellular vesicle transfer of microRNA-223-3p to lung epithelial cells attenuates inflammation in acute lung …
J Chen, S Ma, B Luo, H Hao, Y Li, H Yang… - Journal of …, 2023 - Springer
Background Acute lung injury (ALI), manifested as strong pulmonary inflammation and
alveolar epithelial damage, is a life-threatening disease with high morbidity and mortality …
alveolar epithelial damage, is a life-threatening disease with high morbidity and mortality …
[HTML][HTML] Recent findings regarding the synergistic effects of emodin and its analogs with other bioactive compounds: insights into new mechanisms
Y Hu, L Yang, Y Lai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Context Emodin is a natural bioactive ingredient mainly extracted from traditional Chinese
herbs. Increasing lines of evidence suggest that emodin and its analogs exert notable …
herbs. Increasing lines of evidence suggest that emodin and its analogs exert notable …
Combination of pseudoephedrine and emodin ameliorates LPS-induced acute lung injury by regulating macrophage M1/M2 polarization through the VIP/cAMP/PKA …
WB Wang, JT Li, Y Hui, J Shi, XY Wang, SG Yan - Chinese Medicine, 2022 - Springer
Background Acute lung injury (ALI) is an acute multifactorial infectious disease induced by
trauma, pneumonia, shock, and sepsis. This study aimed to investigate the protective effects …
trauma, pneumonia, shock, and sepsis. This study aimed to investigate the protective effects …
[HTML][HTML] Application of Lung-Targeted Lipid Nanoparticle-delivered mRNA of soluble PD-L1 via SORT Technology in Acute Respiratory Distress Syndrome
H Sun, Y Zhang, J Wang, J Su, D Zhou, X Yu, Y Xu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Acute respiratory distress syndrome (ARDS) is a life-threatening condition
characterized by excessive immune response usually due to lung inflammation. Local …
characterized by excessive immune response usually due to lung inflammation. Local …
Sirtuin 6 regulates macrophage polarization to alleviate sepsis-induced acute respiratory distress syndrome via dual mechanisms dependent on and independent of …
QL Wang, L Yang, ZL Liu, Y Peng, M Gao, LT Deng… - Cytotherapy, 2022 - Elsevier
Background aims Sepsis-induced acute respiratory distress syndrome (ARDS) can be
mediated by an imbalance in macrophage polarization; however, the underlying …
mediated by an imbalance in macrophage polarization; however, the underlying …
Exosomal miR-127-5p from BMSCs alleviated sepsis-related acute lung injury by inhibiting neutrophil extracellular trap formation
XL Zheng, WJ Gu, F Zhang, FZ Zhao, LZ Li… - International …, 2023 - Elsevier
Neutrophil extracellular traps (NETs) play an important role in sepsis-related acute lung
injury (ALI). Bone marrow mesenchymal stem cells (BMSCs)-derived exosomes and miRNA …
injury (ALI). Bone marrow mesenchymal stem cells (BMSCs)-derived exosomes and miRNA …
[HTML][HTML] A novel mechanism for regulating lung immune homeostasis: Zukamu granules alleviated acute lung injury in mice by inhibiting NLRP3 inflammasome …
C Yu, Y Li, Y Li, S Li, F Zeng, J Yu, Z Ji, K Li… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Acute lung injury (ALI) is a severely acute lung
inflammation with high morbidity and mortality. Zukamu granules (ZKMG) is one of the Uygur …
inflammation with high morbidity and mortality. Zukamu granules (ZKMG) is one of the Uygur …