Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis

NC Bal, M Periasamy - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
Thermogenesis in endotherms relies on both shivering and non-shivering thermogenesis
(NST). The role of brown adipose tissue (BAT) in NST is well recognized, but the role of …

[HTML][HTML] The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia

DJ Ham, A Börsch, S Lin, M Thürkauf… - Nature …, 2020 - nature.com
With human median lifespan extending into the 80s in many developed countries, the
societal burden of age-related muscle loss (sarcopenia) is increasing. mTORC1 promotes …

Bacteroides uniformis and its preferred substrate, α-cyclodextrin, enhance endurance exercise performance in mice and human males

H Morita, C Kano, C Ishii, N Kagata, T Ishikawa… - Science …, 2023 - science.org
Although gut microbiota has been linked to exercise, whether alterations in the abundance
of specific bacteria improve exercise performance remains ambiguous. In a cross-sectional …

[HTML][HTML] Ketogenic diet induces skeletal muscle atrophy via reducing muscle protein synthesis and possibly activating proteolysis in mice

R Nakao, T Abe, S Yamamoto, K Oishi - Scientific Reports, 2019 - nature.com
Ketogenic diets (KD) that are very high in fat and low in carbohydrates are thought to
simulate the metabolic effects of starvation. We fed mice with a KD for seven days to assess …

Molecular regulation of brain metabolism underlying circadian epilepsy

F Chan, J Liu - Epilepsia, 2021 - Wiley Online Library
Extensive study has demonstrated that epilepsy occurs with greater frequency at certain
times in the 24‐h cycle. Although these findings implicate an overlap between the circadian …

A ketogenic diet containing medium-chain triglycerides reduces REM sleep duration without significant influence on mouse circadian phenotypes

H Zhuang, Y Fujikura, N Ohkura… - Food Research …, 2023 - Elsevier
Ketogenic diets (KDs) affect the circadian rhythms of behavior and clock gene expression in
experimental animals. However, these diets were designed to simulate a fasting state; thus …

Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia

K Sataranatarajan, G Pharaoh, JL Brown, R Ranjit… - Geroscience, 2020 - Springer
Mice lacking the superoxide anion scavenger CuZn superoxide dismutase (Sod1−/− mice)
develop a number of age-related phenotypes, including an early progression of muscle …

[HTML][HTML] Ketogenic Diet Affects Sleep Architecture in C57BL/6J Wild Type and Fragile X Mice

PR Westmark, AK Gholston, TJ Swietlik… - International Journal of …, 2023 - mdpi.com
Nearly half of children with fragile X syndrome experience sleep problems including trouble
falling asleep and frequent nighttime awakenings. The goals here were to assess sleep …

[HTML][HTML] Comparative analysis of microRNA and mRNA profiles of sperm with different freeze tolerance capacities in boar (Sus scrofa) and giant panda (Ailuropoda …

MX Ran, YM Zhou, K Liang, WC Wang, Y Zhang… - Biomolecules, 2019 - mdpi.com
Post-thawed sperm quality parameters vary across different species after cryopreservation.
To date, the molecular mechanism of sperm cryoinjury, freeze-tolerance and other influential …

[HTML][HTML] A low-carbohydrate ketogenic diet and treadmill training enhanced fatty acid oxidation capacity but did not enhance maximal exercise capacity in mice

S Ma, J Yang, T Tominaga, C Liu, K Suzuki - Nutrients, 2021 - mdpi.com
The low-carbohydrate ketogenic diet (LCKD) is a dietary approach characterized by the
intake of high amounts of fat, a balanced amount of protein, and low carbohydrates, which is …