The beneficial role of rutin, a naturally occurring flavonoid in health promotion and disease prevention: A systematic review and update

K Patel, DK Patel - Bioactive food as dietary interventions for arthritis and …, 2019 - Elsevier
Rutin is a citrus flavonoid glycoside, which is a low molecular weight polyphenolic
compound. There are various physiological functions of rutin and related flavonoids in the …

Polyphenols: multipotent therapeutic agents in neurodegenerative diseases

KS Bhullar, HPV Rupasinghe - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …

Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK–NF-κB pathway

CH Yeh, JJ Yang, ML Yang, YC Li, YH Kuan - Free Radical Biology and …, 2014 - Elsevier
Acute lung injury (ALI) is a serious disease with unacceptably high mortality and morbidity
rates. Up to now, no effective therapeutic strategy for ALI has been established. Rutin …

The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment: the role of oxidative stress

KH Alzoubi, OF Khabour, BA Rashid, IM Damaj… - Behavioural Brain …, 2012 - Elsevier
Sleep deprivation induces oxidative stress and impairs learning and memory processes.
Vitamin E, on the other hand, is a strong antioxidant that has neuroprotective effect on the …

Cell rearrangement and oxidant/antioxidant imbalance in Huntington's disease

F D'Egidio, V Castelli, A Cimini, M d'Angelo - Antioxidants, 2023 - mdpi.com
Huntington's Disease (HD) is a hereditary neurodegenerative disorder caused by the
expansion of a CAG triplet repeat in the HTT gene, resulting in the production of an aberrant …

Radiation protection and mitigation by natural antioxidants and flavonoids: implications to radiotherapy and radiation disasters

R Yahyapour, D Shabeeb, M Cheki… - Current molecular …, 2018 - ingentaconnect.com
Background: Nowadays, ionizing radiations are used for various medical and terroristic
aims. These purposes involve exposure to ionizing radiations. Hence, people are at risk for …

Rutin as a natural therapy for Alzheimer's disease: Insights into its mechanisms of action

S Habtemariam - Current medicinal chemistry, 2016 - ingentaconnect.com
Rutin (quercetin-3-O-rutinoside) is a multifunctional natural flavonoid glycoside with
profound effects on the various cellular functions under pathological conditions. Due to the …

Neuroprotective mechanisms of rutin for spinal cord injury through anti-oxidation and anti-inflammation and inhibition of p38 mitogen activated protein kinase pathway

H Song, X Zhang, W Wang, R Liu, K Zhao… - Neural regeneration …, 2018 - journals.lww.com
Rutin has anti-inflammatory, antioxidant, anti-viral, anti-tumor and immune regulatory effects.
However, the neuroprotective effects of rutin in spinal cord injury are unknown. The p38 …

Coenzyme Q10 regulates antioxidative stress and autophagy in acute myocardial ischemia‐reperfusion injury

S Liang, Z Ping, J Ge - Oxidative Medicine and Cellular …, 2017 - Wiley Online Library
Background. Oxidative stress and autophagy both play key roles in continuous
cardiomyocyte death and cardiac dysfunction after reperfusion therapy for acute myocardial …

Protective effects of antioxidants in Huntington's disease: an extensive review

MM Essa, M Moghadas, T Ba-Omar… - Neurotoxicity …, 2019 - Springer
Huntington's disease (HD) is a hereditary neurodegenerative disease of the central nervous
system (CNS). Onset of HD occurs between the ages of 30 and 50 years, although few …