The development of CETP (cholesteryl ester transfer protein) inhibitors has had a long and
difficult course with 3 compounds failing in phase III clinical trials. Finally, the REVEAL …

The residual risk for arteriosclerotic cardiovascular disease after optimal statin treatment
may amount to 50% and is the consequence of both immunological and lipid disturbances …

Abstract Purpose of Review Cholesteryl ester transfer proteins (CETP) regulate plasma
cholesterol levels by transferring cholesteryl esters (CEs) among lipoproteins. Lipoprotein …

Atherosclerosis is a major contributor to the onset and progression of cardiovascular
disease (CVD). Cholesterol‐loaded foam cells play a pivotal role in forming atherosclerotic …

Raising HDL using cholesteryl ester transfer protein (CETP) inhibitors failed to show a
clinically relevant risk reduction of cardiovascular disease in clinical trials, inviting …

Cholesteryl ester transfer protein (CETP) represents one of the key regulators of the
homeostasis of lipid particles, including high-density lipoprotein (HDL) and low-density …

The cholesteryl ester transfer protein (CETP) system moves cholesteryl esters (CE) from
high density lipoproteins (HDL) to lower density lipoproteins, ie very low-density lipoprotein …

Cholesterol ester transfer protein (CETP) is important clinically and is one of the major
targets in cardiovascular disease studies. With high conformational flexibility, its tunnel …

Human phospholipid transfer protein (PLTP) mediates the transfer of phospholipids among
atheroprotective high-density lipoproteins (HDL) and atherogenic low-density lipoproteins …

Zebrafish have become a powerful model of mammalian lipoprotein metabolism and lipid
cell biology. Most key proteins involved in lipid metabolism, including cholesteryl ester …