Covering: 2016 to 2022 RNA polymerase (RNAP) is the central enzyme in bacterial gene
expression representing an attractive and validated target for antibiotics. Two well-known …

Covering: August 1984 up to January 2022 Worldwide, increasing morbidity and mortality
due to antibiotic-resistant microbial infections has been observed. Therefore, better …

Mycobacterium tuberculosis (MTB) is the main source of tuberculosis (TB), one of the oldest
known diseases in the human population. Despite the drug discovery efforts of past …

Clostridioides difficile (formerly Clostridium difficile) has been regarded as an" urgent threat"
and a significant global health problem, as life-threatening diarrhea and refractory …

Antibiotics are the most crucial drugs for fighting bacterial infection, widely used to treat and
prevent such diseases. Even though these are used against bacterial infections, some …

Polycyclic aromatic hydrocarbons (PAHs), which are widely present in incompletely
combusted air particulate matter< 2.5 μm (PM2. 5), tobacco and other organic materials, can …

Clostridioides difficile (C. difficile) is a gram-positive, spore-forming, anaerobic bacterium
known to be the most common cause of hospital-acquired and antibiotic-associated …

Amidochelocardin is a broad-spectrum antibiotic with activity against many Gram-positive
and Gram-negative bacteria. According to recent data, the antibiotic effect of this atypical …

Clostridioides difficile является наиболее частой причиной антибиотик-
ассоциированной диареи как у стационарных, так и у амбулаторных пациентов, а …

Background: Across the world, antibiotic resistance is a grave problem. To address this
issue, it is necessary to investigate new antibiotic sources. Aim of the study: Egypt's diverse …