[HTML][HTML] Noncoding RNAs in gastric cancer: implications for drug resistance

L Wei, J Sun, N Zhang, Y Zheng, X Wang, L Lv, J Liu… - Molecular cancer, 2020 - Springer
Gastric cancer is the fourth most common malignancy and the third leading cause of cancer-
related deaths worldwide. Advanced gastric cancer patients can notably benefit from …

[HTML][HTML] RhoA signaling in neurodegenerative diseases

SI Schmidt, M Blaabjerg, K Freude, M Meyer - Cells, 2022 - mdpi.com
Ras homolog gene family member A (RhoA) is a small GTPase of the Rho family involved in
regulating multiple signal transduction pathways that influence a diverse range of cellular …

Regulation of RhoA GTPase and various transcription factors in the RhoA pathway

JG Kim, R Islam, JY Cho, H Jeong… - Journal of cellular …, 2018 - Wiley Online Library
RhoA GTPase plays a variety of functions in regulation of cytoskeletal proteins, cellular
morphology, and migration along with various proliferation and transcriptional activity in …

[HTML][HTML] Functions and mechanisms of microRNA-31 in human cancers

T Yu, P Ma, D Wu, Y Shu, W Gao - Biomedicine & Pharmacotherapy, 2018 - Elsevier
MicroRNAs can exhibit opposite functions in different tumors. MiR-31 is a representative
example as it can not only enhance tumor development and progression in pancreatic …

Current and potential biomarkers in gastric cancer: a critical review of the literature

RA de Mello, GA Amaral, NM Neves, EG Lippo… - Future …, 2021 - Taylor & Francis
Gastric cancer is the fourth most common type of cancer worldwide and the second most
lethal. Gastric cancer biomarkers can be used for diagnosis, prediction of sensitivity to …

MicroRNAs in gastric cancer: Biomarkers and therapeutic targets

S Ghafouri-Fard, R Vafaee, H Shoorei, M Taheri - Gene, 2020 - Elsevier
MicroRNAs (miRNAs) are a group of non-coding RNAs that have critical roles in regulation
of expression of genes. They can inhibit or decrease expression of target genes mostly via …

[HTML][HTML] Study of the active ingredients and mechanism of Sparganii rhizoma in gastric cancer based on HPLC-Q-TOF–MS/MS and network pharmacology

X Lu, Y Zheng, F Wen, W Huang, X Chen, S Ruan… - Scientific Reports, 2021 - nature.com
Sparganii rhizoma (SL) has potential therapeutic effects on gastric cancer (GC), but its main
active ingredients and possible anticancer mechanism are still unclear. In this study, we …

MicroRNAs as potential biomarkers for diagnosis, therapy and prognosis of gastric cancer

HL Yuan, T Wang, KH Zhang - OncoTargets and therapy, 2018 - Taylor & Francis
Despite the widespread use of endoscopy and conventional tumor biomarkers, gastric
cancer (GC) remains one of the most frequent causes of cancer-related deaths worldwide …

[HTML][HTML] RHOA in gastric cancer: functional roles and therapeutic potential

S Nam, JH Kim, DH Lee - Frontiers in genetics, 2019 - frontiersin.org
The well-known signal mediator and small GTPase family member, RHOA, has now been
associated with the progression of specific malignancies. In this review, we appraise the …

[HTML][HTML] The role of non-coding RNAs in chemotherapy for gastrointestinal cancers

F Dashti, SMA Mirazimi, N Rabiei, R Fathazam… - … Therapy-Nucleic Acids, 2021 - cell.com
Gastrointestinal (GI) cancers, including colorectal, gastric, hepatic, esophageal, and
pancreatic tumors, are responsible for large numbers of deaths around the world …