Quinazoline compounds have gained significant attention in the fields of agriculture and
chemistry due to their diverse activities. In this study, we focused on a series of quinazoline …

The development of new antimalarials is required because of the threat of resistance to
current antimalarial therapies. To discover new antimalarial chemotypes, we screened the …

Malaria is a very destructive and lethal parasitic disease that causes significant mortality
worldwide, resulting in the loss of millions of lives annually. The uncontrolled intake of …

An efficient methodological approach for the synthesis of a novel series of 4-aryl-8-arylidene-
2-cyanoimino-1, 2, 3, 4, 5, 6, 7, 8-octahydroquinazolines (aryl-CIOHQs) was presented via …

In this study, a series of novel 2, 4, 6-trisubstituted quinazoline derivatives were designed,
synthesized and biologically evaluated their antiproliferative activity against four human …

The clinical resistance towards malarial parasites has rendered many antimalarials
ineffective, likely due to a lack of understanding of time of action and stage specificity of all …

Abstract A series of novel 4, 6, 7-trisubstituted quinazoline derivatives containing
benzothiazole moiety were designed, synthesized and evaluated for their antitumor activity …

Malaria is a devastating disease that causes significant morbidity worldwide. The
development of new antimalarial chemotypes is urgently needed because of the emergence …

This study aims to develop a practical and facile one-pot synthesis of 2-substituted
quinazolines. Using a commercially available and structurally simple ruthenium (II) complex …

Malaria, a disease caused by the Plasmodium parasite, accounts for more than 450000
deaths annually. The devastating impact of this disease is compounded by the emergence …