We report a cobalt‐catalyzed Wagner–Meerwein rearrangement of gem‐disubstituted
allylarenes that generates fluoroalkane products with isolated yields up to 84%. Modification …

Cyclic β, β‐difluoro‐carbonyl compounds have a venerable history as drug discovery leads,
but limitations in the synthesis arsenal continue to impede chemical space exploration. This …

The regio-and enantio-selective dearomatization of phenols has been achieved by I (I)/I (III)
catalysis enabled fluorination. The process is highly para-selective, guiding the fluoride …

The prominence and versatility of propargylic fluorides in medicinal chemistry, coupled with
the potency of F/H and F/OH bioisosterism, has created a powerful impetus to develop …

An electrochemical gem-difluorination of indeno [1, 2-c] furans using commercially available
and easy-to-use triethylamine trihydrofluoride as both the electrolyte and fluorinating agent …

Harnessing the acidity of HF/base reagents is of paramount importance to improve the
efficiency and selectivity of fluorination reactions. Yet, no general method has been reported …

Abstract The 1, 3‐difunctionalization of unactivated alkenes is an under‐explored
transformation that leads to moieties that are otherwise challenging to prepare. Herein, we …

Skeletal editing is an important approach for the modification and diversification of
biologically active molecules. The utilization of nitrogen deletion strategies in skeletal editing …

Fluorination strategies are important in assisting the synthesis of pharmaceuticals. Iodine
(I/III) catalysis has become particularly useful for installing gem-difluoro groups but is limited …

The ability to investigate hypervalent iodine (V) fluorides has been limited primarily by their
difficult preparation traditionally using harsh fluorinating reagents such as trifluoromethyl …