Acinetobacter baumannii Antibiotic Resistance Mechanisms
Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to
public health by causing severe and invasive (mostly nosocomial) infections linked with high …
public health by causing severe and invasive (mostly nosocomial) infections linked with high …
Multidrug efflux pumps: structure, function and regulation
Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly
throughout the world and threaten to become untreatable. The origins of resistance are …
throughout the world and threaten to become untreatable. The origins of resistance are …
Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria
RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …
organisms are diverse in function, energization, and structural organization. They form …
Bacterial multidrug efflux pumps at the frontline of antimicrobial resistance: an overview
L Huang, C Wu, H Gao, C Xu, M Dai, L Huang, H Hao… - Antibiotics, 2022 - mdpi.com
Multidrug efflux pumps function at the frontline to protect bacteria against antimicrobials by
decreasing the intracellular concentration of drugs. This protective barrier consists of a …
decreasing the intracellular concentration of drugs. This protective barrier consists of a …
[HTML][HTML] Understanding the mechanism of bacterial biofilms resistance to antimicrobial agents
A biofilm is a group of microorganisms, that causes health problems for the patients with
indwelling medical devices via attachment of cells to the surface matrix. It increases the …
indwelling medical devices via attachment of cells to the surface matrix. It increases the …
Role of bacterial efflux pumps in biofilm formation
Efflux pumps are widely implicated in antibiotic resistance because they can extrude the
majority of clinically relevant antibiotics from within cells to the extracellular environment …
majority of clinically relevant antibiotics from within cells to the extracellular environment …
A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
Polymyxins remain the last line treatment for multidrug-resistant (MDR) infections. As
polymyxins resistance emerges, there is an urgent need to develop effective antimicrobial …
polymyxins resistance emerges, there is an urgent need to develop effective antimicrobial …
Acinetobacter baumannii biofilms: effects of physicochemical factors, virulence, antibiotic resistance determinants, gene regulation, and future antimicrobial treatments
Acinetobacter baumannii is a leading cause of nosocomial infections due to its increased
antibiotic resistance and virulence. The ability of A. baumannii to form biofilms contributes to …
antibiotic resistance and virulence. The ability of A. baumannii to form biofilms contributes to …
[HTML][HTML] An overview of Acinetobacter baumannii pathogenesis: Motility, adherence and biofilm formation
The Gram-negative opportunistic pathogen Acinetobacter baumannii has gain notoriety in
recent decades, primarily due to its propensity to cause nosocomial infections in critically ill …
recent decades, primarily due to its propensity to cause nosocomial infections in critically ill …