Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration
Recent results from laboratory investigations and clinical trials indicate important roles for
estrogen receptor (ER) agonists in protecting the central nervous system (CNS) from …
estrogen receptor (ER) agonists in protecting the central nervous system (CNS) from …
Estrogen and CD4+ T cells
AB Pernis - Current opinion in rheumatology, 2007 - journals.lww.com
Dissecting the molecular pathways employed by estrogen to modulate CD4+ T cells will be
critical in elucidating the manner by which estrogen exerts its effects on this compartment …
critical in elucidating the manner by which estrogen exerts its effects on this compartment …
GPR30 contributes to estrogen-induced thymic atrophy
C Chunhe, B Dehghani, IJ Magrisso… - Molecular …, 2008 - academic.oup.com
The mechanisms by which prolonged estrogen exposures, such as estrogen therapy and
pregnancy, reduce thymus weight, cellularity, and CD4 and CD8 phenotype expression …
pregnancy, reduce thymus weight, cellularity, and CD4 and CD8 phenotype expression …
Estrogen induces thymic atrophy by eliminating early thymic progenitors and inhibiting proliferation of β-selected thymocytes
AL Zoller, GJ Kersh - The Journal of Immunology, 2006 - journals.aai.org
Although it has been established that high levels of estrogen can induce thymic involution,
the mechanism by which this happens is not known. We have found that daily ip injections of …
the mechanism by which this happens is not known. We have found that daily ip injections of …
Pinocembrin triggers Bax‐dependent mitochondrial apoptosis in colon cancer cells
MAS Kumar, M Nair, PS Hema, J Mohan… - … in cooperation with …, 2007 - Wiley Online Library
Bioflavanoids are the major pigments in plants with multitude of biological activities
including inhibition of proliferation or induction of apoptosis in tumor cells. Eventhough the …
including inhibition of proliferation or induction of apoptosis in tumor cells. Eventhough the …
[HTML][HTML] Estrogens as immunotoxicants: 17α-ethinylestradiol exposure retards thymus development in zebrafish (Danio rerio)
L Kernen, A Phan, J Bo, EL Herzog, J Huynh… - Aquatic toxicology, 2022 - Elsevier
Estrogenic endocrine disrupting compounds (EEDCs) can cause alterations in sexual
development and reproductive function of fish. Growing evidence suggests that EEDCs can …
development and reproductive function of fish. Growing evidence suggests that EEDCs can …
Fas receptor is required for estrogen deficiency-induced bone loss in mice
Bone mass is determined by bone cell differentiation, activity, and death, which mainly occur
through apoptosis. Apoptosis can be triggered by death receptor Fas (CD95), expressed on …
through apoptosis. Apoptosis can be triggered by death receptor Fas (CD95), expressed on …
Age-associated remodeling of thymopoiesis: role for gonadal hormones and catecholamines
G Leposavić, M Perišić - Neuroimmunomodulation, 2008 - karger.com
The present review summarizes recent data on age-related thymic changes termed thymic
involution, and highlights the putative role of perturbances in extrathymical and, possibly …
involution, and highlights the putative role of perturbances in extrathymical and, possibly …
Effect of oestrogen on T cell apoptosis in patients with systemic lupus erythematosus
WU Kim, SY Min, SH Hwang, SA Yoo… - Clinical & …, 2010 - academic.oup.com
Defective control of T cell apoptosis is considered to be one of the pathogenetic
mechanisms in systemic lupus erythematosus (SLE). Oestrogen has been known to …
mechanisms in systemic lupus erythematosus (SLE). Oestrogen has been known to …
The production of alpha/beta and gamma/delta double negative (DN) T-cells and their role in the maintenance of pregnancy
JC Chapman, FM Chapman, SD Michael - Reproductive Biology and …, 2015 - Springer
The ability of the thymus gland to convert bone marrow-derived progenitor cells into single
positive (SP) T-cells is well known. In this review we present evidence that the thymus, in …
positive (SP) T-cells is well known. In this review we present evidence that the thymus, in …