Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

The review lays emphasis on the significance of 1, 2, 3-triazoles synthesized via CuAAC
reaction having potential to act as anti-microbial, anti-cancer, anti-viral, anti-inflammatory …

Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …

Abstract The use of 'Click Reaction'for Cu (I) catalyzed azide–alkyne cycloaddition (CuAAC)
has emerged as one of the most powerful tools for the synthesis of library of organic …

In search of better antibacterial and anticancer agents, a series of novel 4‐[3‐fluoro‐4‐
(morpholin‐4‐yl)] phenyl‐1 H‐1, 2, 3‐triazole derivatives were synthesized (6a‐l and 8a‐j) …

Motivated by evidence garnered from literature probing the use of triazoles in drug discovery
and development, we reported the utilization of bioisosteric replacement and molecular …

Inhibitors of dipeptidyl peptidase-4 (DPP4) have been shown to be effective treatments for
type 2 diabetes. A series of novel 1, 2, 3-triazole based xanthine derivatives were designed …

A copper-catalyzed one-pot synthesis of fused benzothiazino [1, 2, 3] triazolo [4, 5-c]
quinolinone derivatives from 1-iodoalkynes with different aryl azides via an in situ generated …

Abstract A series of novel 1, 2, 3-triazole-2H-benzo [b][1, 4] oxazin-3 (4H)-ones (4a–4k and
5a–5g) were designed, synthesized and screened for their anticancer activity against MCF-7 …

ABSTRACT A series of novel pyrimido [4, 5-c] isoquinolines (3a–3h) and 1, 2, 3-triazole-
coupled pyrimido [4, 5-c] isoquinolines (4a–4h) were synthesized in good to excellent yields …