Spermatogonial stem cells

H Kubota, RL Brinster - Biology of reproduction, 2018 - academic.oup.com
Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

Sheep and goat genome engineering: from random transgenesis to the CRISPR era

P Kalds, S Zhou, B Cai, J Liu, Y Wang… - Frontiers in …, 2019 - frontiersin.org
Sheep and goats are valuable livestock species that have been raised for their production of
meat, milk, fiber, and other by-products. Due to their suitable size, short gestation period …

Sperm viral infection and male infertility: focus on HBV, HCV, HIV, HPV, HSV, HCMV, and AAV

A Garolla, D Pizzol, A Bertoldo, M Menegazzo… - Journal of reproductive …, 2013 - Elsevier
Chronic viral infections can infect sperm and are considered a risk factor in male infertility.
Recent studies have shown that the presence of HIV, HBV or HCV in semen impairs sperm …

MiRNA-20 and mirna-106a regulate spermatogonial stem cell renewal at the post-transcriptional level via targeting STAT3 and Ccnd1

Z He, J Jiang, M Kokkinaki, L Tang, W Zeng… - Stem …, 2013 - academic.oup.com
Studies on spermatogonial stem cells (SSCs) are of unusual significance because they are
the unique stem cells that transmit genetic information to subsequent generations and they …

Viral infections and male infertility: a comprehensive review of the role of oxidative stress

RE Akhigbe, S Dutta, MA Hamed, AF Ajayi… - … in Reproductive Health, 2022 - frontiersin.org
Viral infections have been a part of human existence to date, though viruses have posed a
huge threat with various outbreaks lately. These threats are associated with reproductive …

[HTML][HTML] Production of donor-derived sperm after spermatogonial stem cell transplantation in the dog

Y Kim, D Turner, J Nelson, I Dobrinski… - …, 2008 - rep.bioscientifica.com
Spermatogonial stem cell transplantation (SSCT) offers unique approaches to investigate
SSC and to manipulate the male germline. We report here the first successful performance …

Irradiation enhances the efficiency of testicular germ cell transplantation in sheep

M Herrid, J Olejnik, M Jackson… - Biology of …, 2009 - academic.oup.com
Testis germ cell transplantation in livestock has the potential for production of transgenic
genotypes and for use as an alternative to artificial insemination in animal breeding systems …

Biosafety of recombinant adeno-associated virus vectors

DJ Dismuke, L Tenenbaum… - Current gene …, 2013 - ingentaconnect.com
It is hoped that the use of gene transfer technology to treat both monogenetic and acquired
diseases may soon become a common therapy option in medicine. For gene therapy to …

[HTML][HTML] Induction of spermatogenesis by bone marrow-derived mesenchymal stem cells in busulfan-induced azoospermia in hamster

A Tamadon, D Mehrabani… - … journal of stem …, 2015 - synapse.koreamed.org
Background Bone marrow-derived mesenchymal stem cells (BM-MSCs) have potential of
differentiation and they secrete anti-inflammatory cytokines and growth factors which make …

Viral transduction of male germline stem cells results in transgene transmission after germ cell transplantation in pigs

W Zeng, L Tang, A Bondareva… - Biology of …, 2013 - academic.oup.com
Genetic modification of germline stem cells (GSCs) is an alternative approach to generate
large transgenic animals where transgenic GSCs are transplanted into a recipient testis to …