Woodfordia fruticosa (L.) Kurz: in vitro biotechnological interventions and perspectives

M Aileni, M Bulle, RN Malavath, S Thurpu… - Applied Microbiology …, 2023 - Springer
Woodfordia fruticosa (L.) Kurz is a woody medicinal shrub (Lythraceae) commonly known as
the “fire flame bush.” W. fruticosa plant parts either alone or whole plant have a long history …

Design, synthesis, and pharmacological evaluation of embelin–aryl/alkyl amine hybrids as orally bioavailable blood–brain barrier permeable multitargeted agents with …

VK Nuthakki, S Choudhary, CN Reddy… - ACS chemical …, 2023 - ACS Publications
The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …

[HTML][HTML] Selected natural products in neuroprotective strategies for Alzheimer's disease—a non-systematic review

K Wojtunik-Kulesza, T Oniszczuk, J Mołdoch… - International Journal of …, 2022 - mdpi.com
Neurodegenerative disorders such as Alzheimer's disease (AD) are distinguished by the
irreversible degeneration of central nervous system function and structure. AD is …

Multitargeted C9‐substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and …

R Raghuvanshi, A Jamwal, U Nandi… - Drug Development …, 2023 - Wiley Online Library
Berberrubine is a naturally occurring isoquinoline alkaloid and a bioactive metabolite of
berberine. Berberine exhibits a wide range of pharmacological activities, including …

[HTML][HTML] Evaluation of Inhibitory Activities of Sophora flavescens and Angelica gigas Nakai Root Extracts against Monoamine Oxidases, Cholinesterases, and β …

JE Park, SK Mun, ST Yee, H Kim - Processes, 2022 - mdpi.com
In this study, Sophora flavescens (SF) from Yeongcheon (YSF) and Mt. Jiri (JiSF), and
Angelica gias (AG) from Yeongcheon (YAG), Mt. Jiri (JiAG), and Jecheon (JeAG) were …

Herbal medicines in Alzheimer's disease and the involvement of gut microbiota

M Liu, T Li, H Liang, P Zhong - Frontiers in Pharmacology, 2024 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
memory loss and cognitive impairment. It severely affects the quality of life of victims. The …

[HTML][HTML] Butyrylcholinesterase inhibitory activity of peptides identified from yellow field pea (Pisum sativum) enzymatic protein hydrolysates

ND Asen, OD Okagu, CC Udenigwe… - Journal of Functional …, 2023 - Elsevier
Butyrylcholinesterase (BuChE) is an enzyme implicated in Alzheimer's disease due to the
excessive breakdown of neurotransmitters. The study screened and synthesized de novo …

Mitigating cognitive deficits with teriflunomide: unraveling PI3K-modulated behavioral outcomes in mice

L Singh - Molecular Biology Reports, 2024 - Springer
Background Alzheimer's disease is a leading neurological disorder that gradually impairs
memory and cognitive abilities, ultimately leading to the inability to perform even basic daily …

[PDF][PDF] Some chemical properties and biological activity of an endemic plant Tripleurospermum callosum as a case study

A Aras - Iran. J. Chem. Chem. Eng. Research Article Vol, 2022 - ijcce.ac.ir
T. callosum an endemic plant, used in this study, efficiently inhibited enzymes, with IC50
values of 28.87 mg/mL, 15.75 mg/mL, 36.47 mg/mL, and 60.0 mg/mL, for AChE, BChE, α …

Traditional Herbal Medicine for Dementia Therapy

AE Sosa, Z Hassan - Nutrition in Brain Aging and Dementia, 2024 - Springer
Dementia, a prevalent neurodegenerative disorder, presents a pressing need for alternative
interventions that can alleviate symptoms and enhance the overall quality of life for affected …