Kallikrein-related peptidases (KLKs) are critical regulators of the tumour microenvironment.
KLKs are proteolytic enzymes regulating multiple functions of bioactive molecules including …

The prostate-specific antigen (PSA) blood test is the accepted biomarker of tumor
recurrence. PSA levels in serum correlate with disease progression, though its diagnostic …

The initial part of this review details the controversy behind the use of a serological level of
prostate-specific antigen (PSA) for the diagnostics of prostate cancer (PCa). Novel …

Trypsin and chymotrypsin-like serine proteases from family S1 (clan PA) constitute the
largest protease group in humans and more generally in vertebrates. The prototypes …

Assisted reproductive techniques are routinely used in livestock species to increase and
enhance productivity. Ovarian hyperstimulation is a process that currently relies on …

Background Semen quality is an important index for evaluating male fertility and reflecting
masculine reproductive health. Infertility caused by oligoasthenozoospermia (OAS) has …

Pathophysiological functions of proteins critically depend on both their chemical
composition, including post‐translational modifications, and their three‐dimensional …

A blood clot in brain vessels can cause a stroke, a major cause of death and disability.
Previous research showed that Factor VII Activating Protease (FSAP), a blood protease …

Kallikrein-ähnliche Peptidase 4 beeinflusst die Progression des Prostatakarzinoms. Die
Mechanismen sind weitestgehend ungeklärt. In dieser Arbeit wurde eine differentielle …

To investigate whether the kidney uptake of radiolabeled GLP-1 receptor ligands can be
reduced, short-chained GLP-1R ligands were developed and evaluated in vitro …